DreEX0005287 @ danRer10
Exon Skipping
Gene
ENSDARG00000060053 | KCNH2 (2 of 2)
Description
potassium channel, voltage gated eag related subfamily H, member 2 [Source:HGNC Symbol;Acc:HGNC:6251]
Coordinates
chr24:40293195-40325885:+
Coord C1 exon
chr24:40293195-40293469
Coord A exon
chr24:40322155-40322219
Coord C2 exon
chr24:40325655-40325885
Length
65 bp
Sequences
Splice sites
3' ss Seq
CTCTGTAACTTTCGCTCTAGAGA
3' ss Score
7.27
5' ss Seq
GGGGTGAGT
5' ss Score
7.93
Exon sequences
Seq C1 exon
ATGAGTCCACGAGACCACATTTAAGGGATTACGCGACGCAAAGAGAACACGATTTGAGTTTGGGAAAGTGTTGTTTGGATACACGCATCGCTCGGCGTTCCCGCACGCGCGTCTGATGAAGTTCTCCAGAGCGCGGAAAGAGTGCTGAGAGTGGCGCGAAGGTCAGCCTGAGCTCCGGACTCTCCGCGGGACTCCGAGGATGCCGGTGCGAAGAGGACACGTCGCGCCGCAAAACACTTTCCTCGACACCATCATCAGGAAATTCGAAAGTCAGA
Seq A exon
AGATGATGCAGAGACGGATGAGTTTGCTTCAGTGACACATTAACAACAGAAGTCCATTACCGGGG
Seq C2 exon
GTAGAAAGTTCATCATAGCCAATGCGCGGGTGGAGAACTGCGCCATCATCTTCTGTAACGATGGCTTCTGTCACATGTGCGGCTACACCCGGGCGGAGATCATGCAAAAGCCCTGCACCTGTAACTTTCTGTACGGCCCACACACCAAGCGGCTGGCTATCGCGCAGATGGCGCAGGCGCTGCTGGGCTCCGAGGAGAGGAAGGTGGAGATTGCGCTCTACAGGAAAGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000060053_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.135 A=0.364 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF134261=PAS_9=PU(71.4=96.2)
Main Inclusion Isoform:
ENSDART00000084238fB469
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAAAGAGTGCTGAGAGTGGC
R:
CGCGCATTGGCTATGATGAAC
Band lengths:
169-234
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]