DreEX0064550 @ danRer10
Exon Skipping
Gene
ENSDARG00000018032 | scn8ab
Description
sodium channel, voltage gated, type VIII, alpha subunit b [Source:ZFIN;Acc:ZDB-GENE-060906-2]
Coordinates
chr6:39400405-39410449:-
Coord C1 exon
chr6:39410276-39410449
Coord A exon
chr6:39407253-39407311
Coord C2 exon
chr6:39400405-39400689
Length
59 bp
Sequences
Splice sites
3' ss Seq
GTAACCTTGTCTCTCTATAGTGC
3' ss Score
8.24
5' ss Seq
AGGGTAAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GCATTTGAGGATGTATATATTGAACAGAGGAAAACCATCCAGATCATTCTTGAATATGCAGACAGAGTCTTCACATACATCTTCATCCTGGAAATGTTGCTAAAATGGGTGGCCTATGGGTTTGTCAAATACTTCACCAATGCATGGTGCTGGCTGGACTTCTTCATTGTGGAT
Seq A exon
TGCTGATGGACACAAGAGGGCCTGAGGGGCATAAGAGGGCCGGGAAGTGAGGGGCCAGG
Seq C2 exon
GTTGTGGTGAACGCTTTGGTGGGTGCCATTCCCTCCATCATGAATGTGCTGTTGGTGTGTTTGATCTTTTGGCTGATCTTCAGTATTATGGGTGTCAACCTGTTTGCTGGAAAGTACTATTACTGCTTCAACCAGACTGCAGAGGAGTATTTTCAAGTCGACGTTGTCAATAACAAGACCGAATGCTTTGCACTCATCAATGCAAACTACACAGAAGTTCGCTGGAAGAACGTAAAGATCAATTTCGATAATGTGGGCGCAGGTTACCTGGCACTCTTGCAAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000018032_MULTIEX1-1/2=C1-C2
Average complexity
ME(1-2[98=100])
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PU(17.0=67.2)
A:
PF0052026=Ion_trans=PD(0.1=0.0)
C2:
PF0052026=Ion_trans=FE(40.9=100)
Main Inclusion Isoform:
ENSDART00000151299fB5420
Other Inclusion Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCTGGCTGGACTTCTTCAT
R:
TCCAGCAAACAGGTTGACACC
Band lengths:
139-198
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]