DreEX0065904 @ danRer10
Exon Skipping
Gene
ENSDARG00000104555 | sh2d3cb
Description
SH2 domain containing 3Cb [Source:ZFIN;Acc:ZDB-GENE-040426-1052]
Coordinates
chr5:64450462-64452729:-
Coord C1 exon
chr5:64452296-64452729
Coord A exon
chr5:64450989-64451065
Coord C2 exon
chr5:64450462-64450916
Length
77 bp
Sequences
Splice sites
3' ss Seq
CTTTTTTATGTATTTCCCAGTGA
3' ss Score
8.12
5' ss Seq
CATGTAAGG
5' ss Score
6.57
Exon sequences
Seq C1 exon
GTGTCTGAGTCTCTTGTGCAACAGGAAGGAGATTTTTTAATCCGTGACTCCCTCTCTAGCATTGGAGATTATGTCTTAACCTGCCGCTGGAACCAGAAAGCTCTTCATTTCCTCATCACTAAAGTTTTGCTCAGATCTTATGACACGTACACTCGAGTGCAGTACATTCTGGAGGAGGAGACATTTTATTCTGTCCCGGCGCTGGTTCATTCTTATGTTGGAAATAAAAGGCCTCTGACGAAGAAGAGCGCTGCCTACATTTACTCTCCTGTTAACAGGACACTTCCACTCAGATACCTGGAAACCATGTTTGGGCTGCCGAGTGTGGAGAACAGTCCGGTAAACTCACCAAGCACGCAGAAGGGAAGCCAGAAGAAAAGGGAAAGCGTCGCTGTGACAGAGGCTCTGGAAATCGAGCTGATAAGACCGCAGAC
Seq A exon
TGATGTGGTGAGGAGCTTTGATGGCACCGTGGAGCAGCATGTTGTAGTCTCCACTTCCCCCATATTAATGAGCACAT
Seq C2 exon
TGGCCAGGCGGCGTCGGAGCCCCTCCGGGAACAGAAAGTTTGTAATAATCCCTTCATCACCTGTTCTCAAGTCCAATGAAACACGGCTTTGTTCATCACCTCCTGAAAACACTCTCATCTACTTGGAGCCAACAGTGCATCTTCTGTCCTCCATGACATATCAAAACAGCACAAAATCCAGCTATTCCCACACGACTGACCCTCTTGCTACAAATCATCCCTTTGTGGGACTTGAGATTCAGGCTGTGGATCGCAGAGAGGAGTACGATGAGGATTATTTAGTGCCTTTCACCACAGACATGGTTTCCTGTTTCAGACCTAGCATGTACCAGTCGCCATTTATGCCCCCAGAAAATAAACCTCTGGAGACCAGAATACTGAAAAGGGTGAAGGATGTCCTGTTTGAGGTTGACATAAAGACAATGGCAATGCACATCACCAATATTGACTGCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000104555-'9-9,'9-8,10-9
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.113 A=0.037 C2=0.145
Domain overlap (PFAM):
C1:
PF0001719=SH2=PD(87.7=49.0)
A:
NO
C2:
PF0061714=RasGEF=PU(8.9=11.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGGCTCTGGAAATCGAGCT
R:
AGATGCACTGTTGGCTCCAAG
Band lengths:
178-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]