DreEX6019677 @ danRer10
Exon Skipping
Gene
ENSDARG00000102260 | TMPRSS6
Description
transmembrane protease, serine 6 [Source:HGNC Symbol;Acc:HGNC:16517]
Coordinates
chr6:210035-210628:-
Coord C1 exon
chr6:210460-210628
Coord A exon
chr6:210160-210289
Coord C2 exon
chr6:210035-210155
Length
130 bp
Sequences
Splice sites
3' ss Seq
TGCAGGTATTCCCCATCAGTGTG
3' ss Score
-12.79
5' ss Seq
CTGGCGGCT
5' ss Score
-10.03
Exon sequences
Seq C1 exon
ACTGCGGCCTGAGGCCCTTCAGCAGCCGTATAGTGGGCGGGGCTGATGCAGTGGAGGGGGAGTGGCCATGGCAGGCCAGCCTGCAGATCAGGGGGCGGCACATATGTGGAGGGGCGTTAGTCTCCGCCCAGTGGGTGGTGTCTGCAGCTCACTGTTTCCATGATGACAG
Seq A exon
GTGGACAGTGTATCTGGGTAAGCTGCGTCTGTCCAGCAGTGGTCAGTCAGAGGAGGCGGTGGGCGTCTCGCTCATTCACCTGCATCACTACTATGATGACGAGACTCATGATTACGACGTGGCGCTGCTG
Seq C2 exon
CTGGCGCGGCCGGTGTGGGCGGGTACGCTGGCACAGCCTGTGTGTGTGCCGCCCGTCACGCATCAGCTGGAGCCGGAGCTGCTGTGCTGGGTCACGGGATGGGGAGCGCTCAGAGAGGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000102260-'20-22,'20-21,21-22=AN
Average complexity
A_S
Mappability confidence:
88%=100=75%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(20.6=80.7)
A:
PF0008921=Trypsin=FE(19.3=100)
C2:
PF0008921=Trypsin=FE(17.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCAGCAGCCGTATAGTGGG
R:
ATCCCGTGACCCAGCACAG
Band lengths:
253-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]