GgaEX0004584 @ galGal4
Exon Skipping
Gene
ENSGALG00000003500 | TSC1
Description
tuberous sclerosis 1 [Source:HGNC Symbol;Acc:HGNC:12362]
Coordinates
chr17:6735119-6736821:-
Coord C1 exon
chr17:6736748-6736821
Coord A exon
chr17:6735911-6736135
Coord C2 exon
chr17:6735119-6735297
Length
225 bp
Sequences
Splice sites
3' ss Seq
CTTTTCTCTTGTCTCCACAGGCC
3' ss Score
14.2
5' ss Seq
TTGGTATCT
5' ss Score
0.67
Exon sequences
Seq C1 exon
CCAATGATGGAACATGTGCGAATTCATCCAGAATTAGTGACTGGATCTAAGGACCATGAACTGGACCCACGAAG
Seq A exon
GCCCAGCCACTGAAGAGGAGAAATTGACTCTTGTTGCTGCACAGTAGTGCTCTTGCCCTGCTTTTCAGAGCCACTAGGAAAACACTGCTAAATGGGAACCTATTGAATATCACAGTGCTCAGTTTTGCAGGCTTCTCTCAGACAGGGAGGAGGGGGATGGAGAGAGGGTGGCACCACTGAGGAATTCAGTTGGCACAAAACTACAATTTGAAGCCTTCTGATTTG
Seq C2 exon
GTGGAAAAGACTAGAAACTCATGATGTTGTGATAGAATGTGCCAAAATCTCCCTGGACCCTGCAGAAGCCTCATATGAAGATGGCTATTACTCTGCGTCTCGGAAATCCTGTACAAACTTAAAACATCATCAAACTGACCCCAGTGCCAGCCATTACATTGACACACAGAGCAGCTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSGALG00000003500_CASSETTE4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.227 A=1.000 C2=0.328
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(3.3=100)
A:
PF043887=Hamartin=PD(0.8=40.0)
C2:
PF043887=Hamartin=FE(13.1=100)
Main Inclusion Isoform:
ENSGALT00000005537fB497
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAACATGTGCGAATTCATCCA
R:
TAGCTGCTCTGTGTGTCAATGT
Band lengths:
244-469
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]