HsaEX0000713 @ hg38
Exon Skipping
Gene
ENSG00000143322 | ABL2
Description
ABL proto-oncogene 2, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:77]
Coordinates
chr1:179110282-179112398:-
Coord C1 exon
chr1:179112309-179112398
Coord A exon
chr1:179110575-179110845
Coord C2 exon
chr1:179110282-179110455
Length
271 bp
Sequences
Splice sites
3' ss Seq
TATACCCTGTGATCCACCAGTTC
3' ss Score
6.04
5' ss Seq
CGTGTATGT
5' ss Score
5.08
Exon sequences
Seq C1 exon
GCTGGAAGTGGAGCCCTGCCGATAGGCCCTCTTTTGCTGAAACACACCAAGCTTTTGAAACCATGTTCCATGACTCCAGCATTTCTGAAG
Seq A exon
TTCTCCTACATTGTGCCAATCAGACGTGCATAACATTGTGAACCAAAAGACACAGAGCAGGATGATGCTAGCAACGTATTCATAGTAACTCCAAACTGGAAACAACCTAAACATCCATCAAGAGGAGAACAGGTGGATTGTGGTATATTCACACGTTGGCATGCTACACAGCAATGAGAACCCCTGCCACATGCAGCAGCGTGGACGAATCTACACACATGATACTGGGCGAAAGAAGCCAGACAAAAGAGTACATACTTTATGATTCCGT
Seq C2 exon
AGGTAGCTGAGGAGCTTGGGAGAGCCGCCTCCTCGTCATCTGTTGTTCCATACCTGCCCCGGCTACCTATACTTCCTTCCAAGACTCGGACACTGAAGAAACAGGTGGAGAACAAGGAGAACATTGAAGGGGCACAAGATGCCACAGAAAATTCTGCTTCCAGTTTAGCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143322_MULTIEX1-1/3=C1-2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.538
Domain overlap (PFAM):
C1:
PF0771412=Pkinase_Tyr=PD(7.1=58.1)
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000344730fB66
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGTGGAGCCCTGCCGATAG
R:
CTGGTGCTAAACTGGAAGCA
Band lengths:
260-531
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development