HsaEX0002098 @ hg19
Exon Skipping
Gene
ENSG00000005187 | ACSM3
Description
acyl-CoA synthetase medium-chain family member 3 [Source:HGNC Symbol;Acc:10522]
Coordinates
chr16:20797400-20802010:+
Coord C1 exon
chr16:20797400-20797480
Coord A exon
chr16:20800020-20800094
Coord C2 exon
chr16:20801909-20802010
Length
75 bp
Sequences
Splice sites
3' ss Seq
TCATGTTTAAACATTTTAAGACC
3' ss Score
3.3
5' ss Seq
TCTGTAAGT
5' ss Score
7.96
Exon sequences
Seq C1 exon
GTGCTAATCTGTGGAAATTTTAAGGGAATGAAAATTAAACCTGGCTCAATGGGAAAACCTTCTCCTGCTTTCGATGTTAAG
Seq A exon
ACCCTATGAACAATGAGGAACATGATTCTCCCCAGACACAGAAGATTTTATCTATATTCCCATCTATTAAAATCT
Seq C2 exon
ATTGTAGATGTAAATGGCAATGTTCTACCTCCTGGACAAGAAGGAGATATTGGCATTCAAGTTCTACCCAACCGACCATTTGGCCTTTTTACTCATTACGTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005187-'11-13,'11-12,13-13
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.029
Domain overlap (PFAM):
C1:
PF0050123=AMP-binding=PD(11.1=67.2)
A:
PF0050123=AMP-binding=PD(0.3=33.3)
C2:
PF0050123=AMP-binding=FE(40.5=100),PF131931=AMP-binding_C=PU(11.3=20.0)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTAATCTGTGGAAATTTTAAGGGA
R:
AAAGGCCAAATGGTCGGTTGG
Band lengths:
168-243
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)