HsaEX0002200 @ hg19
Exon Skipping
Gene
ENSG00000135503 | ACVR1B
Description
activin A receptor, type IB [Source:HGNC Symbol;Acc:172]
Coordinates
chr12:52345486-52369288:+
Coord C1 exon
chr12:52345486-52345618
Coord A exon
chr12:52353840-52353971
Coord C2 exon
chr12:52369049-52369288
Length
132 bp
Sequences
Splice sites
3' ss Seq
TGTTCATTTCTGATATCCAGGAT
3' ss Score
6.57
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
CGCTGCTGGGCTGCGGCGGCGGCGGCGGCGGCGGTGGTTACTATGGCGGAGTCGGCCGGAGCCTCCTCCTTCTTCCCCCTTGTTGTCCTCCTGCTCGCCGGCAGCGGCGGGTCCGGGCCCCGGGGGGTCCAGG
Seq A exon
GATGTGCCTAGCACCAAGCTGAATGCTGAGAGGGATCCTGAGGAAAGAGTCTGTCCTTGCCCTTTGGAAGTTTACACACAGAGACCGGCCACAGTGGCTCATGCCTGTAATCCCAACACTTTGGAGAATGAG
Seq C2 exon
CTCTGCTGTGTGCGTGCACCAGCTGCCTCCAGGCCAACTACACGTGTGAGACAGATGGGGCCTGCATGGTTTCCATTTTCAATCTGGATGGGATGGAGCACCATGTGCGCACCTGCATCCCCAAAGTGGAGCTGGTCCCTGCCGGGAAGCCCTTCTACTGCCTGAGCTCGGAGGACCTGCGCAACACCCACTGCTGCTACACTGACTACTGCAACAGGATCGACTTGAGGGTGCCCAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000135503_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=0.333 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0106418=Activin_recp=WD(100=96.3)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCTCCTTCTTCCCCCTTGT
R:
TCCGAGCTCAGGCAGTAGAAG
Band lengths:
243-375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)