HsaEX0002209 @ hg19
Exon Skipping
Gene
ENSG00000121989 | ACVR2A
Description
activin A receptor, type IIA [Source:HGNC Symbol;Acc:173]
Coordinates
chr2:148653870-148657136:+
Coord C1 exon
chr2:148653870-148654077
Coord A exon
chr2:148655810-148655899
Coord C2 exon
chr2:148657027-148657136
Length
90 bp
Sequences
Splice sites
3' ss Seq
ATTTGATTGAAAACAAATAGGAT
3' ss Score
1.48
5' ss Seq
ATGGTGAAA
5' ss Score
0.56
Exon sequences
Seq C1 exon
GTGCTATACTTGGTAGATCAGAAACTCAGGAGTGTCTTTTCTTTAATGCTAATTGGGAAAAAGACAGAACCAATCAAACTGGTGTTGAACCGTGTTATGGTGACAAAGATAAACGGCGGCATTGTTTTGCTACCTGGAAGAATATTTCTGGTTCCATTGAAATAGTGAAACAAGGTTGTTGGCTGGATGATATCAACTGCTATGACAG
Seq A exon
GATAGTAAGAGAAGTAAGAGGAAAAGAAGATTCAAGAATTGTCAAAGTGTGGAAGAAAAGAAAATGATAAAAGAAGAATGAAATTGAATG
Seq C2 exon
GACTGATTGTGTAGAAAAAAAAGACAGCCCTGAAGTATATTTTTGTTGCTGTGAGGGCAATATGTGTAATGAAAAGTTTTCTTATTTTCCGGAGATGGAAGTCACACAGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121989_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.026
Domain overlap (PFAM):
C1:
PF0106418=Activin_recp=PU(65.9=85.7)
A:
PF0106418=Activin_recp=PD(15.8=52.2)
C2:
PF0106418=Activin_recp=PD(33.0=78.9)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGACAAAGATAAACGGCGGCA
R:
ACACATATTGCCCTCACAGCA
Band lengths:
175-265
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)