HsaEX0015308 @ hg19
Exon Skipping
Gene
ENSG00000080644 | CHRNA3
Description
cholinergic receptor, nicotinic, alpha 3 (neuronal) [Source:HGNC Symbol;Acc:1957]
Coordinates
chr15:78885394-78889074:-
Coord C1 exon
chr15:78888882-78889074
Coord A exon
chr15:78886256-78886353
Coord C2 exon
chr15:78885394-78885533
Length
98 bp
Sequences
Splice sites
3' ss Seq
GTTTTGCTCTTGTTGCCCAGGCT
3' ss Score
5.72
5' ss Seq
CAGGTGTGC
5' ss Score
6.46
Exon sequences
Seq C1 exon
ATTCAAGATGATTGGAAGTATGTTGCCATGGTGATTGATCGTATTTTTCTGTGGGTTTTCACCCTGGTGTGCATTCTAGGGACAGCAGGATTGTTTCTGCAACCCCTGATGGCCAGGGAAGATGCATAAGCACTAAGCTGTGTGCCTGCCTGGGAGACTTCCTTGTGTCAGGGCAGGAGGAGGCTGCTTCCTA
Seq A exon
GCTGGAGTGCAATGGCGTGATCTCAGCTCACCGCAACCTCCGCCACCTGGGTTCAAGCGATTCTCCTGCCGCAGCCTCCCAGGTAGCTGGGATTACAG
Seq C2 exon
GAACAAAAAGCCCAAGAGATCCAACAATTGAAACGAAAAGAAAAGTCCACAGAAACATCCGATCAAGAACCTGGGCTATGAATTTCCAATCTTCAACAACCTGTTAGGAAAAAAATAAAAATGCATTAAATAATTGTAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000080644_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.485 C2=1.000
Domain overlap (PFAM):
C1:
PF0293211=Neur_chan_memb=PD(12.5=72.1)
A:
NA
C2:
PF0293211=Neur_chan_memb=PD(4.4=37.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTTCTGCAACCCCTGATGG
R:
GCCCAGGTTCTTGATCGGATG
Band lengths:
178-276
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)