HsaEX0016084 @ hg19
Exon Skipping
Gene
ENSG00000044459 | CNTLN
Description
centlein, centrosomal protein [Source:HGNC Symbol;Acc:23432]
Coordinates
chr9:17388160-17395067:+
Coord C1 exon
chr9:17388160-17388251
Coord A exon
chr9:17389959-17390100
Coord C2 exon
chr9:17394532-17395067
Length
142 bp
Sequences
Splice sites
3' ss Seq
GTGTCTTTATTTAAAAAAAGGAA
3' ss Score
3.51
5' ss Seq
AATGTGAGA
5' ss Score
3.37
Exon sequences
Seq C1 exon
AACAGCTCTTTAGATCTGGTGAAGATGATGAGGTCAAGAGGAGTACTCCAGAGAAGAATGGAAAAGAAATGTTGGAGCAGACATTACAGAAG
Seq A exon
GAAATTAGAATACAGACAAATACAGAGGGAAGTCCATGTGAAGACACAGGGAAAAGATAGCCATTTACAAGCCAAGGAGAAAGGCCTCAGAAGAAACCAACCCTGCTGACACCTTGATCTTGGACTTCTAGACTCCAGGAAT
Seq C2 exon
GTCACTGAGTTGGAAAATCGGCTGAAATCTTTTGAGAAAAGGTCGAGAAAATTAAAAGAAGGGAATAAAAAATTAATGAAAGAAAATGATTTTCTGAAATCCCTCTTAAAACAGCAACAAGAAGATACAGAGACCAGAGAAAAAGAGCTAGAACAGATAATAAAGGGGAGTAAAGATGTAGAAAAAGAAAATACTGAACTTCAAGTAAAAATCAGTGAGCTGGAGACAGAAGTCACTTCCCTGAGGAGACAAGTGGCAGAAGCTAATGCATTGAGAAATGAAAATGAAGAGCTGATCAACCCAATGGAGAAATCACACCAGTCAGCAGACAGAGCTAAATCCGAGATGGCCACCATGAAAGTGAGATCTGGACGATATGATTGTAAGACAACTATGACCAAGGTTAAATTTAAAGCTGCGAAGAAAAATTGCTCTGTGGGTCGTCACCACACTGTTCTCAATCATTCCATCAAGGTTATGAGCAATGTGTTTGAGAACCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000044459-'25-24,'25-23,26-24
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.880 A=1.000 C2=0.659
Domain overlap (PFAM):
C1:
PF0003816=Filament=PU(2.8=12.9)
A:
NO
C2:
PF0003816=Filament=PD(95.7=75.4)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTGGAGCAGACATTACAGAAG
R:
TGACTTCTGTCTCCAGCTCACT
Band lengths:
258-400
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)