HsaEX0016086 @ hg19
Exon Skipping
Gene
ENSG00000044459 | CNTLN
Description
centlein, centrosomal protein [Source:HGNC Symbol;Acc:23432]
Coordinates
chr9:17236407-17273864:+
Coord C1 exon
chr9:17236407-17236586
Coord A exon
chr9:17239061-17239295
Coord C2 exon
chr9:17273731-17273864
Length
235 bp
Sequences
Splice sites
3' ss Seq
TGTTCGTTTGTTTGAGACAGAGT
3' ss Score
1.26
5' ss Seq
ACGGTGAGC
5' ss Score
9.44
Exon sequences
Seq C1 exon
GACACTAAGGAGTGTGTACAGAACAAAGAAGAGCAAAACAGACTAGTTATAAAAAATCTGGAGGAGGAAAACAAGAAATTAAGTACCCGCTGCACTGACCTGCTAAATGACCTGGAGAAATTGAGGAAGCAGGAAGCACATTTGAGAAAAGAAAAATATAGCACTGATGCAAAAATAAAG
Seq A exon
AGTCTTGCTCTGTTGCCCAGGCTGGAATACAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCCTTCCCGGGTTCAAGCTATTCTCCTCCCGAGAAGAGGCAAATTACTACAGGCGCGTGCCACCACATGCAGATAATTTGTGTATTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTGGAATCATTGTGGTTTTGATTTGCATTTTCCTGATGGGAAATGACG
Seq C2 exon
ACCTTTGAAGACAATTTAATTGAAGCAAGGAAAGAAGTTGAAGTATCACAGAGTAAATACAATGCTCTATCATTACAGTTGAGTAATAAACAGACTGAACTTATCCAGAAGGATATGGATATTACCCTGGTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000044459-'7-9,'7-7,8-9
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.063 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF061568=DUF972=PD(20.3=25.0)
A:
PF139001=GVQW=WD(100=40.5)
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGTGTACAGAACAAAGAAGAGCA
R:
CCAGGGTAATATCCATATCCTTCTGG
Band lengths:
300-535
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)