HsaEX0016846 @ hg38
Exon Skipping
Gene
ENSG00000145244 | CORIN
Description
corin, serine peptidase [Source:HGNC Symbol;Acc:HGNC:19012]
Coordinates
chr4:47692970-47744583:-
Coord C1 exon
chr4:47744402-47744583
Coord A exon
chr4:47722453-47722578
Coord C2 exon
chr4:47692970-47693083
Length
126 bp
Sequences
Splice sites
3' ss Seq
CTTCAAATATTTTCCTTCAGGAA
3' ss Score
9.09
5' ss Seq
CAGGTTTGA
5' ss Score
5.11
Exon sequences
Seq C1 exon
TCATGGACTCCTGCCCTGTAGGTCCTTCTGTGAGGCTGCAAAAGAAGGCTGTGAATCAGTCCTGGGGATGGTGAATTACTCCTGGCCGGATTTCCTCAGATGCTCCCAGTTTAGAAACCAAACTGAAAGCAGCAATGTCAGCAGAATTTGCTTCTCACCTCAGCAGGAAAACGGAAAGCAAT
Seq A exon
GAACAATATCTTCTCTGACAACATTTGGAGAATGAGGAGGCAGGATAGCAAGATGGAAGATATTTTAAATTGTCTATGTGTTTGGAACTCCAGATGTTTTATACCCAGGAGCATGTGCCATAGCAG
Seq C2 exon
TGCTCTGTGGAAGGGGTGAGAACTTTCTGTGTGCCAGTGGAATCTGCATCCCCGGGAAACTGCAATGTAATGGCTACAACGACTGTGACGACTGGAGTGACGAGGCTCATTGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145244_MULTIEX1-1/9=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0139217=Fz=PD(42.9=82.3)
A:
NA
C2:
PF0005713=Ldl_recept_a=WD(100=94.9),PF0005713=Ldl_recept_a=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATGGACTCCTGCCCTGTAG
R:
TTACATTGCAGTTTCCCGGGG
Band lengths:
252-378
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development