HsaEX0018273 @ hg38
Exon Skipping
Gene
ENSG00000138115 | CYP2C8
Description
cytochrome P450 family 2 subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:2622]
Coordinates
chr10:95038897-95043077:-
Coord C1 exon
chr10:95042890-95043077
Coord A exon
chr10:95040922-95040960
Coord C2 exon
chr10:95038897-95039038
Length
39 bp
Sequences
Splice sites
3' ss Seq
CCTCAAAATTTTCTTTTCAGAGC
3' ss Score
8.66
5' ss Seq
TAGGTGAGA
5' ss Score
6.95
Exon sequences
Seq C1 exon
CTAAAGTCCAGGAAGAGATTGATCATGTAATTGGCAGACACAGGAGCCCCTGCATGCAGGATAGGAGCCACATGCCTTACACTGATGCTGTAGTGCACGAGATCCAGAGATACAGTGACCTTGTCCCCACCGGTGTGCCCCATGCAGTGACCACTGATACTAAGTTCAGAAACTACCTCATCCCCAAG
Seq A exon
AGCTTTGATAACAAGATAATGCTGGCTGCATAAAACTAG
Seq C2 exon
GGCACAACCATAATGGCATTACTGACTTCCGTGCTACATGATGACAAAGAATTTCCTAATCCAAATATCTTTGACCCTGGCCACTTTCTAGATAAGAATGGCAACTTTAAGAAAAGTGACTACTTCATGCCTTTCTCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138115_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.098 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(13.5=100)
A:
PF0006717=p450=PD(1.9=63.6)
C2:
PF0006717=p450=FE(10.3=100)
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACAGTGACCTTGTCCCCACC
R:
TGTCATCATGTAGCACGGAAG
Band lengths:
124-163
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development