HsaEX0019473 @ hg19
Exon Skipping
Gene
ENSG00000149091 | DGKZ
Description
diacylglycerol kinase, zeta [Source:HGNC Symbol;Acc:2857]
Coordinates
chr11:46389555-46391100:+
Coord C1 exon
chr11:46389555-46389629
Coord A exon
chr11:46389728-46389853
Coord C2 exon
chr11:46391044-46391100
Length
126 bp
Sequences
Splice sites
3' ss Seq
TTATACAAACGGCCTGCCAGGAG
3' ss Score
3.88
5' ss Seq
TGGGTTCGT
5' ss Score
0.72
Exon sequences
Seq C1 exon
AAGTCAGTGTCTCGAAGAAAGTGCGCAGCCTGCAAGATTGTGGTGCACACGCCCTGCATCGAGCAGCTGGAGAAG
Seq A exon
GAGTGACCCAGCACTCGGGGGTGAAGAGTCAAGGACCCTGGAGCCAAATGCCTGCGTTCGAATCCTGGCTCCTCACTGATTAGCTGCTGTATCCCCACTGCCTGGAACAAACCTGGCGCCTAGTGG
Seq C2 exon
ATAAATTTCCGCTGTAAGCCGTCCTTCCGTGAATCAGGCTCCAGGAATGTCCGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000149091_MULTIEX1-3/3=2-C2
Average complexity
C2
Mappability confidence:
88%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.053
Domain overlap (PFAM):
C1:
PF0013017=C1_1=FE(42.9=100)
A:
PF0013017=C1_1=PD(0.1=0.0)
C2:
PF0013017=C1_1=PD(10.3=31.6),PF0013017=C1_1=PU(0.1=0.0)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTCAGTGTCTCGAAGAAAGTGC
R:
CTCGCGGACATTCCTGGAG
Band lengths:
131-257
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)