HsaEX0021872 @ hg19
Exon Skipping
Gene
ENSG00000181090 | EHMT1
Description
euchromatic histone-lysine N-methyltransferase 1 [Source:HGNC Symbol;Acc:24650]
Coordinates
chr9:140695332-140706067:+
Coord C1 exon
chr9:140695332-140695436
Coord A exon
chr9:140697309-140697804
Coord C2 exon
chr9:140705913-140706067
Length
496 bp
Sequences
Splice sites
3' ss Seq
TCTTTCCCACTGCGGGTTAGGAT
3' ss Score
5.19
5' ss Seq
CAGGTGATC
5' ss Score
4.28
Exon sequences
Seq C1 exon
GATGACGGAGGCTGGACACCCATGATCTGGGCCACAGAGTACAAGCACGTGGACCTCGTGAAGCTGCTGCTGTCCAAGGGCTCTGACATCAACATCCGAGACAAC
Seq A exon
GATGACGGCACCATGAAGAGAGGAGCCCTGAGCCGGCAGAAGGAAGAGAAGAGGGAAGCAGAGGAGCCCTGAGCTGGTGGAAGGCTGTGGCGGGTACCTTGGAGGAAGAGAGGAGGGAAGCAAAGGCAGAGAACAAGGCAGAGGCCACCCCCAGGTGGGGCCACCTCACCCACCGCCCCCGGAGACTGCGTGGCGGGGAAGGCGGCCCTAGTGTGGCTGGTCGGCCTGCATGCCTGGGCAGTTTGCAGCCTGTCCAGGTGTCAGAGCTGTTAGCTCTCTGATGCTGGTGGCTGTTCCCCCAGAATGGAAGCATTGATTAAATTTCAAGTTTGTTATTTATACAATGAAACACTTCATTAATTTAACCACTTTATTGCTGTATAATAGGTAGGCTGCATATATTCAAAGTACACACTTGGGTGAATTTTCACCCAGAAGCCATTGTTGCTGTCGGAAGAGTGAGCCCAGTCCTCCCTCATGCCCTGATGATCTTCAG
Seq C2 exon
GAGGAGAACATTTGCCTGCACTGGGCGGCGTTCTCCGGCTGCGTGGACATAGCCGAGATCCTGCTGGCTGCCAAGTGCGACCTCCACGCCGTGAACATCCACGGAGACTCGCCACTGCACATTGCCGCCCGGGAGAACCGCTACGACTGTGTCGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000181090_MULTIEX2-1/8=C1-2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.012 A=1.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(35.1=94.3)
A:
NO
C2:
PF127962=Ank_2=PU(51.7=88.5)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGACGGAGGCTGGACACC
R:
GACACAGTCGTAGCGGTTCTC
Band lengths:
258-754
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)