HsaEX0023630 @ hg38
Exon Skipping
Gene
ENSG00000088926 | F11
Description
coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529]
Coordinates
chr4:186280474-186284260:+
Coord C1 exon
chr4:186280474-186280580
Coord A exon
chr4:186281935-186281987
Coord C2 exon
chr4:186284092-186284260
Length
53 bp
Sequences
Splice sites
3' ss Seq
AACAGACTATGCCTTCCTAGAGC
3' ss Score
4.38
5' ss Seq
AAAGCAAGT
5' ss Score
1.97
Exon sequences
Seq C1 exon
GGGCAAGTGTTACTTAAAGCTTTCTTCAAACGGATCTCCAACTAAAATACTTCACGGGAGAGGAGGCATCTCTGGATACACATTAAGGTTGTGTAAAATGGATAATG
Seq A exon
AGCTTAGAGGCGCTCCGATGAAAATCTCTGGATGGCTCAAGACTTCTTAAAAA
Seq C2 exon
AGTGTACCACCAAAATCAAGCCCAGGATCGTTGGAGGAACTGCGTCTGTTCGTGGTGAGTGGCCGTGGCAGGTGACCCTGCACACAACCTCACCCACTCAGAGACACCTGTGTGGAGGCTCCATCATTGGAAACCAGTGGATATTAACAGCCGCTCACTGTTTCTATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000088926_CASSETTE2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF142951=PAN_4=PD(11.8=16.2)
A:
NO
C2:
PF0008921=Trypsin=PU(20.3=82.5)
Main Inclusion Isoform:
ENST00000403665fB2485
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGAGGAGGCATCTCTGGAT
R:
GAGGTTGTGTGCAGGGTCAC
Band lengths:
142-195
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development