HsaEX0025067 @ hg38
Exon Skipping
Gene
ENSG00000138829 | FBN2
Description
fibrillin 2 [Source:HGNC Symbol;Acc:HGNC:3604]
Coordinates
chr5:128305511-128307203:-
Coord C1 exon
chr5:128307135-128307203
Coord A exon
chr5:128305823-128305948
Coord C2 exon
chr5:128305511-128305636
Length
126 bp
Sequences
Splice sites
3' ss Seq
CCAAATCTGTTCCATTTCAGACA
3' ss Score
7.35
5' ss Seq
AAGGTAATC
5' ss Score
7.46
Exon sequences
Seq C1 exon
CTGACTTTAAAACCATATGTGGAAATATTCCTGGATTCACCTTTGACATTCACACAGGAAAAGCTGTTG
Seq A exon
ACATTGATGAATGTAAAGAGATTCCAGGCATTTGTGCAAATGGTGTGTGCATTAACCAGATTGGCAGTTTCCGCTGTGAATGCCCTACAGGATTCAGTTACAATGACCTGCTGTTGGTTTGTGAAG
Seq C2 exon
ATATAGATGAGTGCAGCAATGGTGATAATCTCTGCCAGCGGAATGCAGACTGCATCAATAGTCCTGGTAGTTACCGCTGTGAATGTGCCGCGGGTTTCAAACTTTCACCCAATGGGGCCTGTGTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138829-'74-89,'74-88,75-89
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0068312=TB=PD(11.4=20.8),PF0764510=EGF_CA=PU(0.1=0.0)
A:
PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)
C2:
PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATTCCTGGATTCACCTTTGACA
R:
CTACACAGGCCCCATTGG
Band lengths:
170-296
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development