HsaEX0026037 @ hg38
Exon Skipping
Gene
ENSG00000157827 | FMNL2
Description
formin like 2 [Source:HGNC Symbol;Acc:HGNC:18267]
Coordinates
chr2:152632008-152636590:+
Coord C1 exon
chr2:152632008-152632137
Coord A exon
chr2:152633453-152633651
Coord C2 exon
chr2:152636427-152636590
Length
199 bp
Sequences
Splice sites
3' ss Seq
TATCTTTCTATTTCTCTCAGCCC
3' ss Score
7.5
5' ss Seq
ACAGTAGGC
5' ss Score
2.69
Exon sequences
Seq C1 exon
CTCTTAGATACAAAGTCAACAGACAGAAAGCAAACACTGTTGCACTATATATCCAATGTGGTGAAAGAAAAATATCACCAAGTGTCCCTGTTTTATAATGAGCTTCATTATGTGGAAAAAGCTGCTGCAG
Seq A exon
CCCCTGAAAATTGGATGTTGGAAATAAATGAATGAACAAGTGAACAAATGAATGAATGAGATGATGCACTGTTACAGGGACAAATGCTGCAGAAGCTGTGGTGGAGACTGAGAGGCAGATGGAGATGACTCTCTGACTATGAAGAACTATATGACGCAGGCTGGATAGACCTAGAGCAAGTTCGGGGCTCACTTAGACA
Seq C2 exon
TCTCCCTTGAGAATGTTTTGCTGGATGTCAAGGAGCTCCAGAGGGGAATGGACTTGACCAAGAGAGAGTACACCATGCATGACCATAACACGCTGCTGAAGGAGTTCATCCTCAACAATGAGGGGAAGCTGAAGAAGCTGCAGGATGATGCCAAGATCGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157827_CASSETTE3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.015
Domain overlap (PFAM):
C1:
PF0218118=FH2=FE(11.7=100)
A:
PF0218118=FH2=PD(0.7=16.7)
C2:
PF0218118=FH2=FE(14.7=100)
Main Inclusion Isoform:
ENST00000288670fB2772
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAAAGCAAACACTGTTGCACT
R:
GGCATCATCCTGCAGCTTCTT
Band lengths:
258-457
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development