HsaEX0030075 @ hg19
Exon Skipping
Gene
ENSG00000156515 | HK1
Description
hexokinase 1 [Source:HGNC Symbol;Acc:4922]
Coordinates
chr10:71055389-71103745:+
Coord C1 exon
chr10:71055389-71055436
Coord A exon
chr10:71060525-71060617
Coord C2 exon
chr10:71103583-71103745
Length
93 bp
Sequences
Splice sites
3' ss Seq
GTGTTTGTCTCTCTTTTCAGCAT
3' ss Score
12.14
5' ss Seq
TTTGTACGT
5' ss Score
3.25
Exon sequences
Seq C1 exon
GCTACAGCAGCTGAAAAACCAAAACTTCATCTACTTGCTGAAAGTGAG
Seq A exon
CATTGTTGATGCTCTTGAGAGCATCAGCCAGGACATTAATGTGCACCACTGTGGTGGCGTGGAAAGATGGCAAAAAGAGCCCTGCATGATTTT
Seq C2 exon
ATTGACAAGTATCTCTATGCCATGCGGCTCTCCGATGAAACTCTCATAGATATCATGACTCGCTTCAGGAAGGAGATGAAGAATGGCCTCTCCCGGGATTTTAATCCAACAGCCACAGTCAAGATGTTGCCAACATTCGTAAGGTCCATTCCTGATGGCTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156515_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. ATG)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.135 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=PU(2.0=25.0),PF0481510=Sec23_helical=PU(13.6=50.0)
A:
PF0034916=Hexokinase_1=PU(2.4=55.6),PF0481510=Sec23_helical=PU(13.6=88.9)
C2:
PF0034916=Hexokinase_1=FE(26.2=100),PF0481510=Sec23_helical=PD(89.1=89.1)
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGCAGCTGAAAAACCAAAACT
R:
GGCAACATCTTGACTGTGGCT
Band lengths:
176-269
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)