HsaEX0035240 @ hg38
Exon Skipping
Gene
ENSG00000053747 | LAMA3
Description
laminin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6483]
Coordinates
chr18:23847464-23857988:+
Coord C1 exon
chr18:23847464-23847668
Coord A exon
chr18:23851381-23851573
Coord C2 exon
chr18:23857844-23857988
Length
193 bp
Sequences
Splice sites
3' ss Seq
TTTTCTCCTTCTGCCTCCAGACC
3' ss Score
11.52
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
Exon sequences
Seq C1 exon
CGTGCAGCTGTGGTCGGCGCCTTTGTGAAGAGATGACGGGGCAGTGCCGCTGCCCTCCCCGCACGGTCAGGCCCCAGTGTGAGGTGTGTGAGACACACTCATTCAGCTTCCACCCCATGGCCGGCTGCGAAGGCTGCAACTGTTCCAGGAGGGGCACCATCGAGGCTGCCATGCCGGAGTGTGACCGGGACAGCGGGCAGTGCAG
Seq A exon
ACCAAGAAGATGTGTGGTGTGAGTTGCGTCCTGTCTCTGCCGCTCACTCTCTGGGTGACCTCAGGTATATTACTTCTGTCCTCTGGGCCTTAGGTCTTCATCTGTAAAATAAGGATCCTGGAGGCACCTTTAGAGGGTTAAATATCCTCTGTGAACACACTGAAAGCAGCGCCTGATACACTCTGAGCACCCA
Seq C2 exon
ATGCAAGCCCAGAATCACAGGGCGGCAGTGTGACCGATGTGCTTCCGGGTTTTACCGCTTTCCTGAGTGTGTTCCCTGCAATTGCAACAGAGATGGGACTGAGCCAGGAGTGTGTGACCCAGGGACCGGGGCTTGCCTCTGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000053747_CASSETTE7
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(6.1=4.3),PF0005319=Laminin_EGF=PU(46.9=33.3)
A:
NO
C2:
PF0005319=Laminin_EGF=PD(51.0=51.0),PF0005319=Laminin_EGF=PU(44.9=44.9)
Main Inclusion Isoform:
ENST00000313654fB3805
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCGCCTTTGTGAAGAGATGA
R:
TAAAACCCGGAAGCACATCGG
Band lengths:
244-437
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development