HsaEX0035265 @ hg38
Exon Skipping
Gene
ENSG00000130702 | LAMA5
Description
laminin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6485]
Coordinates
chr20:62318843-62319795:-
Coord C1 exon
chr20:62319684-62319795
Coord A exon
chr20:62319443-62319569
Coord C2 exon
chr20:62318843-62319013
Length
127 bp
Sequences
Splice sites
3' ss Seq
AGGCAGGATCTGTCTTTTAGATG
3' ss Score
3.73
5' ss Seq
CCGGTTAGA
5' ss Score
3.29
Exon sequences
Seq C1 exon
GCCGTGGGGACCCGAGACCAGGCGAGCCAATTGCTGGCCGGCACCGAGGCCACACTGGGCCATGCGAAGACGCTGTTGGCGGCCATCCGGGCTGTGGACCGCACCCTGAGCG
Seq A exon
ATGGGAGACGACGCCTCTGGAGTGAACAGTAGGGCAGGGTCAGGAGGTCGGCGACACAGCCGTGTGGCCAGACAGGTGGCCCCGGGAGACGTCAGACCCCTCGACAGCCTCCCCAGGAAATGTGCCG
Seq C2 exon
AGCTCATGTCCCAGACGGGCCACCTGGGGCTGGCCAATGCCTCGGCTCCATCAGGTGAGCAGCTGCTCCGGACACTGGCCGAGGTGGAGCGGCTGCTCTGGGAGATGCGGGCCCGGGACCTGGGGGCCCCGCAGGCAGCAGCTGAGGCTGAGTTGGCTGCAGCACAGAGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130702_CASSETTE6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.105 A=0.200 C2=0.207
Domain overlap (PFAM):
C1:
PF060089=Laminin_I=FE(14.0=100)
A:
PF060089=Laminin_I=PD(0.1=0.0)
C2:
PF060089=Laminin_I=FE(21.5=100)
Main Inclusion Isoform:
ENST00000252999fB3807
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGACCAGGCGAGCCAATTG
R:
CAGCCAACTCAGCCTCAGC
Band lengths:
258-385
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development