HsaEX0035278 @ hg19
Exon Skipping
Gene
ENSG00000091136 | LAMB1
Description
laminin, beta 1 [Source:HGNC Symbol;Acc:6486]
Coordinates
chr7:107575860-107577722:-
Coord C1 exon
chr7:107577538-107577722
Coord A exon
chr7:107576724-107576818
Coord C2 exon
chr7:107575860-107576101
Length
95 bp
Sequences
Splice sites
3' ss Seq
TCTTTCTTTCTTTCTTTAAGAGA
3' ss Score
8.76
5' ss Seq
GAGGTGAAC
5' ss Score
4.07
Exon sequences
Seq C1 exon
GAAACTGATTAAAGATGTTACAGAAATGATGGCTCAAGTAGAAGTGAAATTATCTGACACAACTTCCCAAAGCAACAGCACAGCCAAAGAACTGGATTCTCTACAGACAGAAGCCGAAAGCCTAGACAACACTGTGAAAGAACTTGCTGAACAACTGGAATTTATCAAAAACTCAGATATTCGGG
Seq A exon
AGATGGGCTCTTGCTATGCTGCTCAGGCTGGTCTTGAACTCCTGGACTCAAGTGATCCTCCCGTCTCAGACTTCTGAATAGCTGAGATTATAGAG
Seq C2 exon
GTGCCTTGGATAGCATTACCAAGTATTTCCAGATGTCTCTTGAGGCAGAGGAGAGGGTGAATGCCTCCACCACAGAACCCAACAGCACTGTGGAGCAGTCAGCCCTCATGAGAGACAGAGTAGAAGACGTGATGATGGAGCGAGAATCCCAGTTCAAGGAAAAACAAGAGGAGCAGGCTCGCCTCCTTGATGAACTGGCAGGCAAGCTACAAAGCCTAGACCTTTCAGCCGCTGCCGAAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091136-'37-42,'37-41,39-42
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.455 A=0.280 C2=0.617
Domain overlap (PFAM):
C1:
PF041117=APG6=FE(43.4=100),PF0154413=CorA=FE(47.3=100),PF061607=EzrA=PD(55.8=84.1),PF057146=Borrelia_lipo_1=FE(51.7=100),PF0157614=Myosin_tail_1=PD(51.7=96.8),PF0001516=MCPsignal=PD(61.9=95.2),PF064286=Sec2p=FE(84.9=100),PF0003816=Filament=FE(58.5=100)
A:
PF041117=APG6=PD(1.4=7.7),PF0154413=CorA=PD(1.5=7.7),PF057146=Borrelia_lipo_1=PD(0.8=3.8),PF064286=Sec2p=PD(2.7=7.7),PF0003816=Filament=PD(4.7=19.2)
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCACAGCCAAAGAACTGGA
R:
ATTCACCCTCTCCTCTGCCTC
Band lengths:
172-267
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)