HsaEX0036146 @ hg19
Exon Skipping
Gene
ENSG00000129038 | LOXL1
Description
lysyl oxidase-like 1 [Source:HGNC Symbol;Acc:6665]
Coordinates
chr15:74235195-74238895:+
Coord C1 exon
chr15:74235195-74235303
Coord A exon
chr15:74237508-74237781
Coord C2 exon
chr15:74238758-74238895
Length
274 bp
Sequences
Splice sites
3' ss Seq
CCTTTTCCTTTTGTCACAAGGCC
3' ss Score
6.72
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
GTCTCCCTGACTTGGTCCCAGACCCCAACTATGTGCAAGCATCCACTTATGTGCAGAGAGCCCACCTGTACTCCCTGCGCTGTGCTGCGGAGGAGAAGTGTCTGGCCAG
Seq A exon
GCCTACCTCAGTTGGAAATCTGGAGTCAGCAGGTGACTTGCGAGCAGGCAATTCATACCAGACCCATGTTCCCTGAATGGAAAAGGGCAGGTTGCCAGCCTGAAGCCATGCAATCAGGGAGAGGTGGTCTGGACCCAGTGCAAGATGTAGATGGTATCGGGCTGTGCTGCAGTCAGTGCTGTTAGAGCTCACAGGCAATCCGGATCCTCTATGTAGAGCAATCAGGGCAGACTTCCTGGAGGAGGGGACTTTTGAGTTGACCCTAGGATACTGG
Seq C2 exon
CACAGCCTATGCCCCTGAGGCCACCGACTACGATGTGCGGGTGCTACTGCGCTTCCCCCAGCGCGTGAAGAACCAGGGCACAGCAGACTTCCTCCCCAACCGGCCACGGCACACCTGGGAGTGGCACAGCTGCCACCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000129038-'4-6,'4-5,6-6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.360 A=0.920 C2=0.106
Domain overlap (PFAM):
C1:
PF0118612=Lysyl_oxidase=PU(16.6=91.9)
A:
PF0118612=Lysyl_oxidase=PD(28.6=53.8)
C2:
PF0118612=Lysyl_oxidase=FE(22.4=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCCTGACTTGGTCCCAGAC
R:
CTGTGCCACTCCCAGGTGT
Band lengths:
236-510
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)