HsaEX0036452 @ hg19
Exon Skipping
Gene
ENSG00000162337 | LRP5
Description
low density lipoprotein receptor-related protein 5 [Source:HGNC Symbol;Acc:6697]
Coordinates
chr11:68170951-68174281:+
Coord C1 exon
chr11:68170951-68171167
Coord A exon
chr11:68171691-68171884
Coord C2 exon
chr11:68173992-68174281
Length
194 bp
Sequences
Splice sites
3' ss Seq
ATTTGTCTCTTCCTGAAAAGGTG
3' ss Score
8.04
5' ss Seq
TGGGTGAGA
5' ss Score
6.04
Exon sequences
Seq C1 exon
GTGATCAATGTTGATGGGACGAAGAGGCGGACCCTCCTGGAGGACAAGCTCCCGCACATTTTTGGGTTCACGCTGCTGGGGGACTTCATCTACTGGACTGACTGGCAGCGCCGCAGCATCGAGCGGGTGCACAAGGTCAAGGCCAGCCGGGACGTCATCATTGACCAGCTGCCCGACCTGATGGGGCTCAAAGCTGTGAATGTGGCCAAGGTCGTCG
Seq A exon
GTGACAGAGTTACACTGGAGAGAGCAGCATCCAGGTGCGGCAGGGACAGGCCTGGGGCTCGCGGGCAGGGACTCTGTGTCCTGCCGGGGTCCCACACTGCACCTGCTTGTCAGAGGCACTCAGTCAATCTTTGCTGATGAAGGATGAGAGGACAGAGGACGTGATGCTTGCTGCTGCATTGCCTGCAGTCCTGG
Seq C2 exon
GAACCAACCCGTGTGCGGACAGGAACGGGGGGTGCAGCCACCTGTGCTTCTTCACACCCCACGCAACCCGGTGTGGCTGCCCCATCGGCCTGGAGCTGCTGAGTGACATGAAGACCTGCATCGTGCCTGAGGCCTTCTTGGTCTTCACCAGCAGAGCCGCCATCCACAGGATCTCCCTCGAGACCAATAACAACGACGTGGCCATCCCGCTCACGGGCGTCAAGGAGGCCTCAGCCCTGGACTTTGATGTGTCCAACAACCACATCTACTGGACAGACGTCAGCCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337_CASSETTE4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(61.5=32.9)
A:
NO
C2:
PF146701=FXa_inhibition=WD(100=37.1),PF0005812=Ldl_recept_b=PU(24.4=10.3)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGGGGCTCAAAGCTGTGAA
R:
GGATGGCCACGTCGTTGTTAT
Band lengths:
245-439
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)