HsaEX0036453 @ hg38
Exon Skipping
Gene
ENSG00000162337 | LRP5
Description
LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]
Coordinates
chr11:68446436-68449275:+
Coord C1 exon
chr11:68446436-68446533
Coord A exon
chr11:68446927-68447157
Coord C2 exon
chr11:68448809-68449275
Length
231 bp
Sequences
Splice sites
3' ss Seq
TGGTGGCTCTGTCCTCTTAGGAT
3' ss Score
8.97
5' ss Seq
CAGGTGTGC
5' ss Score
6.46
Exon sequences
Seq C1 exon
ATCCTGAACCCGCCGCCCTCCCCGGCCACGGACCCCTCCCTGTACAACATGGACATGTTCTACTCTTCAAACATTCCGGCCACTGCGAGACCGTACAG
Seq A exon
GATGGGACAAGTCTGTGAAGGCTGCTGCAGCACCCACCGTAGACCCCTAATCGTGTGACGTCACCAGGATGGTCCGGGCTGCTCACTTGCCACAGTGGCCTGTTTGAGCCCGGGAAGCCAACGGGGCTGCTCAGCTGGACACCAGCCCCCCGAGCTGCCCATGTTGGGGTCACAGGCCCCACCTCCCTGGTTGGGGAGGGGCAACTGAGAGTGTGGAGAGGTGGGACCCAG
Seq C2 exon
GCCCTACATCATTCGAGGAATGGCGCCCCCGACGACGCCCTGCAGCACCGACGTGTGTGACAGCGACTACAGCGCCAGCCGCTGGAAGGCCAGCAAGTACTACCTGGATTTGAACTCGGACTCAGACCCCTATCCACCCCCACCCACGCCCCACAGCCAGTACCTGTCGGCGGAGGACAGCTGCCCGCCCTCGCCCGCCACCGAGAGGAGCTACTTCCATCTCTTCCCGCCCCCTCCGTCCCCCTGCACGGACTCATCCTGACCTCGGCCGGGCCACTCTGGCTTCTCTGTGCCCCTGTAAATAGTTTTAAATATGAACAAAGAAAAAAATATATTTTATGATTTAAAAAATAAATATAATTGGGATTTTAAAAACATGAGAAATGTGAACTGTGATGGGGTGGGCAGGGCTGGGAGAACTTTGTACAGTGGAGAAATATTTATAAACTTAATTTTGTAAAACAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337_CASSETTE6
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.120 A=0.000 C2=0.319
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000294304fB3958
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCTCCCTGTACAACATGGA
R:
GGGCGGGAAGAGATGGAAGTA
Band lengths:
298-529
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development