HsaEX0036926 @ hg38
Exon Skipping
Gene
ENSG00000168056 | LTBP3
Description
latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:HGNC:6716]
Coordinates
chr11:65547439-65548045:-
Coord C1 exon
chr11:65547920-65548045
Coord A exon
chr11:65547694-65547821
Coord C2 exon
chr11:65547439-65547567
Length
128 bp
Sequences
Splice sites
3' ss Seq
GGCCTACCCGTTCTTCTCAGATG
3' ss Score
7.4
5' ss Seq
TGCGTGGGT
5' ss Score
-0.08
Exon sequences
Seq C1 exon
AGACTGATGAGTGCCGACTGAACCAGAACATCTGTGGCCACGGAGAGTGCGTGCCGGGCCCCCCTGACTACTCCTGCCACTGCAACCCCGGCTACCGGTCACATCCCCAGCACCGCTACTGCGTGG
Seq A exon
ATGTGAACGAGTGCGAGGCAGAGCCCTGTGGCCCGGGGAGGGGCATCTGCATGAACACCGGCGGCTCCTACAATTGCCACTGCAACCGCGGCTACCGCCTGCACGTGGGCGCCGGGGGGCGCTCGTGC
Seq C2 exon
ACCTGAACGAATGCGCCAAGCCCCACCTGTGCGGCGACGGCGGCTTCTGCATCAACTTTCCCGGTCACTACAAGTGCAACTGCTACCCCGGCTACCGGCTCAAAGCCTCCCGGCCTCCTGTGTGCGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168056-'25-39,'25-38,26-39
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.026 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=WD(100=67.4),PF0764510=EGF_CA=PU(0.1=0.0)
A:
PF0764510=EGF_CA=WD(100=95.6),PF0764510=EGF_CA=PU(0.1=0.0)
C2:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGAGTGCCGACTGAACCAG
R:
CTTCGCACACAGGAGGCC
Band lengths:
250-378
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development