HsaEX0038739 @ hg38
Exon Skipping
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3506108-3507923:-
Coord C1 exon
chr1:3507795-3507923
Coord A exon
chr1:3507434-3507548
Coord C2 exon
chr1:3506108-3507026
Length
115 bp
Sequences
Splice sites
3' ss Seq
ACTGTTGCTAATTTTCCCAGGGC
3' ss Score
6.63
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
Exon sequences
Seq C1 exon
CTTGTCCTCCGGACACCTTTGGGAAGAACTGCAGCTTCTCCTGCAGCTGTCAGAATGGTGGGACCTGCGACTCTGTCACGGGGGCCTGCCGCTGCCCCCCGGGTGTCAGTGGAACTAACTGTGAGGATG
Seq A exon
GGCCTAACTGTAGCAGACGATAAGACTACAGAGCAGCACTTTTGGAATGGGTTCCCTTGAGAGGCAGTGAGGTCCCTGTTCCTGGAAGCATTCAAGTAGAGCTGGTGATGGCTGG
Seq C2 exon
GGTGCTGGGGAACCCCCGTATTCATTCCTGGGTGCTGCACCCCTGGGATCGTGCTGTACCCTCCAGGCTGCCTGCAGCGTTGAGGGGTCACCTCCCCTTCTCCAGGCCTCCTCTTTCTGTCTCGGCTTCCGCCTGCCTCTCAGATGAGGATGTTTGTCTTTGGATTCAGGGCCAGCCTGGATAATGTAGGGCTACTATGGCAAGCACTGTTGCAAGAAATGCAACTGTGCCTAGTCTCCAGGTCCTGGGGACTAGGACGTGTATGTAGTTGTGGGGGTACCTTCAGCTGACTACCGCCTTCAGTAGGAGGAAGGACGTGGGGCAGGACCCAGCCAGAGAGAATTGTTTGGGGAAGAAAGGCGAGGACCTTTCTAGCTCTGGGGCCACCTGCGGCTTGGGCCTGGGACCTTGTCTACTGGGGCCACGTGTCCTTCCCGCTTTGAGGCTCTGAGATCAAGCTTAGTGACCACCAGGGGACAGAAGTCAGGCGGCTCCTGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-'43-36,'43-35,44-36
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(63.8=68.2)
A:
PF0005319=Laminin_EGF=PD(12.5=62.5)
C2:
PF0005319=Laminin_EGF=PD(34.0=36.4)
Main Inclusion Isoform:
ENST00000356575fB4227
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTTTGGGAAGAACTGCAGC
R:
AGCCGAGACAGAAAGAGGAGG
Band lengths:
242-357
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development