HsaEX0038746 @ hg38
Exon Skipping
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3496655-3497361:-
Coord C1 exon
chr1:3497233-3497361
Coord A exon
chr1:3496988-3497119
Coord C2 exon
chr1:3496655-3496783
Length
132 bp
Sequences
Splice sites
3' ss Seq
CCCTGCCTGTCTCCACCCAGCCT
3' ss Score
7.84
5' ss Seq
AACGTGAGT
5' ss Score
9.54
Exon sequences
Seq C1 exon
CCTGCCTGCGGGGCTGGTTTGGAGAGGCCTGTGCCCAGCGCTGCAGCTGCCCGCCTGGCGCTGCCTGCCACCACGTCACTGGGGCCTGCCGCTGTCCCCCTGGCTTCACTGGCTCCGGCTGCGAGCAGG
Seq A exon
CCTGCCCACCCGGCAGCTTTGGGGAGGACTGTGCGCAGATGTGCCAGTGTCCCGGTGAGAACCCGGCCTGCCACCCTGCCACCGGGACCTGCTCATGTGCTGCTGGCTACCACGGCCCCAGCTGCCAGCAAC
Seq C2 exon
GATGTCCGCCCGGGCGGTATGGGCCAGGCTGTGAACAGCTGTGTGGGTGTCTCAACGGGGGCTCCTGTGATGCGGCCACGGGGGCCTGCCGCTGCCCCACTGGGTTCCTCGGGACGGACTGCAACCTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.051 A=0.239 C2=0.236
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(67.4=65.9)
A:
PF0005319=Laminin_EGF=PD(30.2=28.9),PF0005319=Laminin_EGF=PU(63.8=66.7)
C2:
PF0005319=Laminin_EGF=PD(34.0=36.4)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGTTTGGAGAGGCCTGTG
R:
TGAGGTTGCAGTCCGTCCC
Band lengths:
245-377
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development