HsaEX0039534 @ hg19
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:21827762-21846111:+
Coord C1 exon
chr10:21827762-21827841
Coord A exon
chr10:21840745-21840850
Coord C2 exon
chr10:21845572-21846111
Length
106 bp
Sequences
Splice sites
3' ss Seq
CTCTCTTTTTTTTTTTTTAGGCA
3' ss Score
12.03
5' ss Seq
CAAGTAGGT
5' ss Score
7.33
Exon sequences
Seq C1 exon
CTTGCTATGGCATTGTTCAAGTACCCACTGGACCGTGGTTTTGCAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
Seq A exon
GCAGAGTCTCGCTCTGTTGCCCAGGCTAAAGTGCAGTGGTGTGATCTCAGCCCACTGCAACCTCTGCTCCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAA
Seq C2 exon
ATGGTATGCAATTCCTGTTGGTTAGCCTCATCTGAAAACGTCACTCCTGGATACATAGAACATCACTGCGCATGTGCATCTCCCCACCCCCGATGCCTGGTGTCTAACGTTCCTCCAGTTTCTGGTGCTCTGATGCATTGCTTTTGGGCTTGTCTTACTACAGCAGCTTTCTTCGGTCCTCAGTCATTTACCACTTGTCATATGTCCTTTCTAGTTTCCAGGGATATTCTTTTTTATATTTATGGCTTTATGCCATTTATCTCAGTTGTCATTTGGCGTTTCAAGAAGGAGAGGTGGTAGTGTTTAAGTGGAATTAACTACTTGTGTTTCTGATGTGGTCTTTTATATTTCTTACAGGGTTTTGTTTTACCAAGTACTAGTCTTCAGTCTATCCTGTTTACTTGATTTTTTCCCACTCAACTCACAAACATTTTTGAATCATCTCATGAATTCTGCTTTCCATTTACATTTTTGCCCTTTTGTCTTTTCCTCTTCGCTGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403-'4-8,'4-7,8-8
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
A:
PF139001=GVQW=PU(83.3=83.3)
C2:
PF139001=GVQW=PD(13.9=41.7)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCAAGTACCCACTGGACCGT
R:
GAGGACCGAAGAAAGCTGCTG
Band lengths:
246-352
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)