HsaEX0039541 @ hg38
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:HGNC Symbol;Acc:HGNC:16063]
Coordinates
chr10:21538833-21586348:+
Coord C1 exon
chr10:21538833-21538912
Coord A exon
chr10:21571975-21572026
Coord C2 exon
chr10:21586294-21586348
Length
52 bp
Sequences
Splice sites
3' ss Seq
ATCAGTGTTTTCTTTTGTAGTTA
3' ss Score
7.61
5' ss Seq
AAGGTAATT
5' ss Score
8.83
Exon sequences
Seq C1 exon
CTTGCTATGGCATTGTTCAAGTACCCACTGGACCGTGGTTTTGCAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTG
Seq A exon
TTATTGCTTACTGTGAGCTAAGACAGTTTTGCCTAACCTCGAAGTCATGAAG
Seq C2 exon
AGATGTGAACTTTGTCCCCATAAGGATGGAGCTTTAAAAAGAACAGATAATGGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403_MULTIEX1-8/11=3-9
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF138311=PHD_2=PD(48.6=66.7),PF138321=zf-HC5HC2H_2=PU(0.1=0.0)
A:
NA
C2:
PF138321=zf-HC5HC2H_2=FE(15.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTATGGCATTGTTCAAGTACCC
R:
CCCCATTATCTGTTCTTTTTAAAGCT
Band lengths:
132-184
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development