HsaEX0039546 @ hg19
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:21940602-21959633:+
Coord C1 exon
chr10:21940602-21940697
Coord A exon
chr10:21957846-21957981
Coord C2 exon
chr10:21959378-21959633
Length
136 bp
Sequences
Splice sites
3' ss Seq
TGACTTTTAAACTTCACTAGGTC
3' ss Score
7.84
5' ss Seq
AAAGTAAGC
5' ss Score
7.31
Exon sequences
Seq C1 exon
AAATATAAAGAGAAGGACAAACACAAACAGAAACACAAGAAGCAGCCAGAACCATCACCTGCATTGGTTCCATCCTTGACTGTTACTACAGAAAAA
Seq A exon
GTCATGCAAGGATCAGATGTGAGAGGAATGGAGAACCTCAGGATCAACTCAAGTAATTGGAAAAAGTATTTGAAAAATGAGGTGGGGTGGTTTCCAAATTGACCTGCCCAGCATGGAAAAGGTTCATATTTCTAAA
Seq C2 exon
ACTTATACAAGCACTAGCAACAACTCTATATCTGGATCATTGAAGCGCTTGGAAGATACTACTGCACGATTTACAAATGCAAATTTCCAGGAAGTCTCTGCACACACCTCTAGTGGAAAAGATGTTTCAGAGACTAGAGGGTCAGAGGGCAAAGGGAAGAAATCTTCAGCTCACAGCTCAGGTCAAAGGGGAAGAAAGCCTGGTGGTGGAAGAAATCCAGGAACAACTGTGTCAGCAGCTAGCCCTTTTCCTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403_MULTIEX3-2/8=C1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.994 A=0.394 C2=1.000
Domain overlap (PFAM):
C1:
PF105004=SR-25=PD(24.0=56.2)
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACAAGAAGCAGCCAGAACCA
R:
CCTTTGACCTGAGCTGTGAGC
Band lengths:
252-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)