HsaEX0041183 @ hg19
Exon Skipping
Gene
ENSG00000197535 | MYO5A
Description
myosin VA (heavy chain 12, myoxin) [Source:HGNC Symbol;Acc:7602]
Coordinates
chr15:52703373-52708498:-
Coord C1 exon
chr15:52708342-52708498
Coord A exon
chr15:52707313-52707399
Coord C2 exon
chr15:52703373-52703473
Length
87 bp
Sequences
Splice sites
3' ss Seq
TGTCTTTTTCCTTTGTCAAGCTT
3' ss Score
5.78
5' ss Seq
GAGGTAATT
5' ss Score
8.88
Exon sequences
Seq C1 exon
AGATGAACGAAATCAGTCCATCATCGTAAGTGGAGAGTCTGGGGCAGGAAAAACAGTCTCAGCTAAGTATGCCATGCGATACTTTGCAACTGTGAGTGGTTCTGCCAGTGAGGCCAATGTGGAGGAAAAGGTCTTGGCCTCCAACCCCATCATGGAG
Seq A exon
CTTTATTTGTCACCCAAACACAGATGGAGTTAAAATCGGCCTGGTGCACCTGTGGTACAAGTGGTTTTTGCGATAATCTATGTAGAG
Seq C2 exon
GATAAGGTGATAGAAACATCAGGCTAAAGAGACCCTGAACACCAGAGCAGCATTTCCAGGAAATATTCATTGGTCTTAACCATCTTATTTATGTAAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197535-'13-14,'13-13,14-14
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.375
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(38.0=100)
A:
PF0006316=Myosin_head=PD(4.3=54.5)
C2:
PF0006316=Myosin_head=PD(1.5=22.2)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTGGGGCAGGAAAAACAGT
R:
AATGCTGCTCTGGTGTTCAGG
Band lengths:
175-262
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)