HsaEX0041246 @ hg38
Exon Skipping
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77190697-77192278:+
Coord C1 exon
chr11:77190697-77190870
Coord A exon
chr11:77191675-77191782
Coord C2 exon
chr11:77192051-77192278
Length
108 bp
Sequences
Splice sites
3' ss Seq
GATTTTGCCTCCACCCCCAGCAA
3' ss Score
6.58
5' ss Seq
CAGGTACTG
5' ss Score
9.04
Exon sequences
Seq C1 exon
GCCACCAAGTCCAAGAAGCCAATCATGTTGCCCGTGACATTCATGGATGGGACCACCAAGACCCTGCTGACGGACTCGGCAACCACGGCCAAGGAGCTCTGCAACGCGCTGGCCGACAAGATCTCTCTCAAGGACCGGTTCGGGTTCTCCCTCTACATTGCCCTGTTTGACAAG
Seq A exon
CAACGTCATGCTCAGCAGAGGGGCCCCCGCCCACAAGCCCAGGGGAGGTACCGTGTTGCTGGACACAGTTTGCCTGGATTTTTCTCACCGATGCTCTTATGTTTCCAG
Seq C2 exon
GTGTCCTCCCTGGGCAGCGGCAGTGACCACGTCATGGACGCCATCTCCCAGTGCGAGCAGTACGCCAAGGAGCAGGGCGCCCAGGAGCGCAACGCCCCCTGGAGGCTCTTCTTCCGCAAAGAGGTCTTCACGCCCTGGCACAGCCCCTCCGAGGACAACGTGGCCACCAACCTCATCTACCAGCAGGTGGTGCGAGGAGTCAAGTTTGGGGAGTACAGGTGTGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474_MULTIEX1-1/23=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.361 C2=0.013
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=PD(1.9=3.4),PF093795=FERM_N=PU(50.5=79.3)
A:
PF093795=FERM_N=FE(27.8=100)
C2:
PF093795=FERM_N=PD(47.3=56.6)
Main Inclusion Isoform:
ENST00000409619fB4507
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCTCTCAAGGACCGGTTCG
R:
CCACCTGCTGGTAGATGAGGT
Band lengths:
243-351
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development