HsaEX0045425 @ hg19
Exon Skipping
Gene
ENSG00000100767 | PAPLN
Description
papilin, proteoglycan-like sulfated glycoprotein [Source:HGNC Symbol;Acc:19262]
Coordinates
chr14:73730353-73731043:+
Coord C1 exon
chr14:73730353-73730490
Coord A exon
chr14:73730650-73730752
Coord C2 exon
chr14:73730919-73731043
Length
103 bp
Sequences
Splice sites
3' ss Seq
CCCCCTACCCCCTCTGACAGGTG
3' ss Score
10.54
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
Exon sequences
Seq C1 exon
GATTAGCTTGGCAGGTGTGGAGCCCTCGTTGGTGCAGGCAGCCCTGGGGCAGTTGGTGCGGCTCTCCTGCTCAGACGACACTGCCCCGGAATCCCAGGCTGCCTGGCAGAAAGATGGCCAGCCCATCTCCTCTGACAG
Seq A exon
GTGTGTGTGACGGCCCCCCGACCTCCTCTGACAGGTGTGTGTGACAGCCCCCCGACCTCCTCTGACAGGTTCACGTGACAGCTCCCTCCACCTCCGCTGACAG
Seq C2 exon
GCACAGGCTGCAGTTCGACGGATCCCTGATCATCCACCCCCTGCAGGCAGAGGACGCGGGCACCTACAGCTGTGGCAGCACCCGGCCAGGCCGCGACTCCCAGAAGATCCAACTTCGCATCATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100767_MULTIEX3-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.599 A=1.000 C2=0.556
Domain overlap (PFAM):
C1:
PF0767911=I-set=PU(50.0=87.2)
A:
NO
C2:
PF0767911=I-set=PD(48.8=93.0)
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTAGCTTGGCAGGTGTGGAG
R:
GTTGGATCTTCTGGGAGTCGC
Band lengths:
250-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)