HsaEX0046166 @ hg38
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]
Coordinates
chr6:165388298-165392796:-
Coord C1 exon
chr6:165392646-165392796
Coord A exon
chr6:165390886-165390982
Coord C2 exon
chr6:165388298-165388453
Length
97 bp
Sequences
Splice sites
3' ss Seq
CTCTTGAGATTTCTTATCAGGTA
3' ss Score
5.11
5' ss Seq
CAGGCGAGT
5' ss Score
2.92
Exon sequences
Seq C1 exon
CTTTGAGCTTGAAAAGTTGTGTCGTTTTATTATGTCTGTGAAGAAGAACTATCGGCGGGTTCCTTATCACAACTGGAAGCATGCGGTCACTGTAGCACACTGCATGTATGCCATACTTCAGAACAATCACACGCTTTTCACAGACCTTGAG
Seq A exon
GTACATCATGATGACACAGCAGCATATAACATGGAAACCACCCCAAAACAAAATGATACTAACAACATAATTAATTCAGTTATCTTAAGAATGCCAG
Seq C2 exon
CGCAAAGGACTGCTGATTGCGTGTCTGTGTCATGACCTGGACCACAGGGGCTTCAGTAACAGCTACCTGCAGAAGTTCGACCACCCTCTGGCCGCTCTCTACTCCACTTCCACCATGGAGCAGCACCACTTCTCCCAGACTGTGTCCATCCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541_MULTIEX2-1/2=C1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.121 C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=PU(11.9=54.9)
A:
NO
C2:
PF0023314=PDEase_I=FE(21.6=100)
Main Inclusion Isoform:
ENST00000366882fB5051
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGAACTATCGGCGGGTTCC
R:
GCTGTTACTGAAGCCCCTGTG
Band lengths:
172-269
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development