HsaEX0046860 @ hg19
Exon Skipping
Gene
ENSG00000087157 | PGS1
Description
phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:30029]
Coordinates
chr17:76410960-76415756:+
Coord C1 exon
chr17:76410960-76411108
Coord A exon
chr17:76413183-76413302
Coord C2 exon
chr17:76415627-76415756
Length
120 bp
Sequences
Splice sites
3' ss Seq
AGCTTCCTGGTTTTGTTCAGGGA
3' ss Score
6.39
5' ss Seq
CTGGTAATT
5' ss Score
5.99
Exon sequences
Seq C1 exon
GCCTCTGGCTGTACCTGGCAGGGAGCAGCCTGCCCTGTCTCACGCTGATTGGCTCTCCTAATTTTGGGTACAGGTCAGTTCACCGGGACCTGGAGGCCCAGATTGCGATCGTGACGGAGAACCAGGCCCTGCAGCAGCAGCTTCACCAG
Seq A exon
GGAACACAGTTTACCACTTGTGACCCAAGAAAGACTCCCTCGAACAGCGTCGTAACCTCGTCAGCTGACTTCCTTCTCCATCCCTGTTGTGGAGTCTGTGAGGAAACCTAAGTGTTTCTG
Seq C2 exon
GAGCAAGAGCAGCTCTACCTGAGGTCAGGTGTGGTGTCCTCTGCCACCTTCGAGCAGCCGAGTCGCCAGGTGAAGCTGTGGGTGAAGATGGTGACTCCACTGATCAAGAACTTCTTCTGAGGACAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087157-'11-15,'11-14,12-15
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.056 C2=0.101
Domain overlap (PFAM):
C1:
PF130911=PLDc_2=FE(28.8=100)
A:
PF130911=PLDc_2=PD(1.8=8.1)
C2:
PF130911=PLDc_2=PD(2.9=12.5)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTCTGGCTGTACCTGGCA
R:
GTCACCATCTTCACCCACAGC
Band lengths:
243-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)