HsaEX0047673 @ hg38
Exon Skipping
Gene
ENSG00000186088 | GSAP
Description
gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042]
Coordinates
chr7:77377286-77381354:-
Coord C1 exon
chr7:77381305-77381354
Coord A exon
chr7:77379847-77380000
Coord C2 exon
chr7:77377286-77377390
Length
154 bp
Sequences
Splice sites
3' ss Seq
TGATTTTCTTCAATATTTAGTCT
3' ss Score
6.06
5' ss Seq
AAAGTATGT
5' ss Score
6.93
Exon sequences
Seq C1 exon
ATATTGAACAATTTCGTATCCATGTCGCCCAAGAAGATGGAAATAGAGTG
Seq A exon
TCTGCATCAAAATTGTCTCTGAAGATTTTAACATTTCTCTGAAGATTTTAAAGTTAAGTGAACAAATTGAAACAGAAAATGGAATTTATCAATTGTGTATCAGCTATTGAAAGCCTCAAATCAAGAAGCCTGGCTGGAAAATTGCCAGGAGAAA
Seq C2 exon
GTGATTAAAAATTCTGGCCATCTCCCAAGAGACAGAATAGCTGAGGATTTCGTTTGGGCTCAGTGGGATATGTCAGAACAGAGATTATATTACATTGACCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186088_MULTIEX6-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000257626fB5235
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATTGAACAATTTCGTATCCATGTCG
R:
TATAATCTCTGTTCTGACATATCCCA
Band lengths:
138-292
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development