HsaEX0052265 @ hg19
Exon Skipping
Gene
ENSG00000079337 | RAPGEF3
Description
Rap guanine nucleotide exchange factor (GEF) 3 [Source:HGNC Symbol;Acc:16629]
Coordinates
chr12:48132926-48133974:-
Coord C1 exon
chr12:48133924-48133974
Coord A exon
chr12:48133154-48133201
Coord C2 exon
chr12:48132926-48133013
Length
48 bp
Sequences
Splice sites
3' ss Seq
ACTGCTGTGAATTTTCTCAGTGC
3' ss Score
5.94
5' ss Seq
TGGGTGAGA
5' ss Score
6.04
Exon sequences
Seq C1 exon
CGGCTGCCTCACAAAGTCCGGAAGCTGTACTCCGCCCTCGAGAGGCTGCTG
Seq A exon
TGCTAATGGGAGGTTGGAAGCCCCGTGTTCGCCTGTGACAGAGCCTGG
Seq C2 exon
GATCCCTCATGGAACCACCGGGTATACCGACTGGCCCTCGCCAAGCTCTCCCCTCCTGTCATCCCCTTCATGCCCCTTCTTCTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079337_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=FE(12.7=100),PF136131=HTH_Tnp_4=PD(27.3=50.0)
A:
PF0061714=RasGEF=PD(0.7=33.3)
C2:
PF0061714=RasGEF=FE(15.6=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCCTCACAAAGTCCGGAAG
R:
GAGAAGAAGGGGCATGAAGGG
Band lengths:
132-180
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)