HsaEX0052281 @ hg19
Exon Skipping
Gene
ENSG00000136237 | RAPGEF5
Description
Rap guanine nucleotide exchange factor (GEF) 5 [Source:HGNC Symbol;Acc:16862]
Coordinates
chr7:22349588-22355095:-
Coord C1 exon
chr7:22354989-22355095
Coord A exon
chr7:22354193-22354253
Coord C2 exon
chr7:22349588-22349709
Length
61 bp
Sequences
Splice sites
3' ss Seq
ATCACTATTCTATTTCAAAGAAA
3' ss Score
3.97
5' ss Seq
AAAGTAGGA
5' ss Score
3.63
Exon sequences
Seq C1 exon
ATTTATGGAGAGAATTCTTCTTGTGCAGGAAGAGCATTGAGGAATATTATTATCGTTCAAGCAGCTGACCTGATAAAGGACAGAGTGAACCTCAAGGGGTTTTACAG
Seq A exon
AAATGACGTGCAATACCCATCAAGAGTAAGAAGAGGACTCAGGATTCATGACACCCAAAAA
Seq C2 exon
GAGGAGCTGCGTTGGGTCAGAGCTGGTAGACTGGCTTCTAGAACACTGTCCTTTCGTCCAGTGCAGATCTATGGCCATAGGAGTCTGGCAACTCCTACTGGACATGGGAATTATGTTATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136237-'4-6,'4-4,5-6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.028 A=0.143 C2=0.000
Domain overlap (PFAM):
C1:
PF0061016=DEP=PU(17.4=33.3)
A:
NO
C2:
PF0061016=DEP=PU(51.5=94.4)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCGTTCAAGCAGCTGACCTG
R:
TGGCCATAGATCTGCACTGGA
Band lengths:
133-194
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)