HsaEX0052284 @ hg19
Exon Skipping
Gene
ENSG00000136237 | RAPGEF5
Description
Rap guanine nucleotide exchange factor (GEF) 5 [Source:HGNC Symbol;Acc:16862]
Coordinates
chr7:22206691-22233073:-
Coord C1 exon
chr7:22232985-22233073
Coord A exon
chr7:22231147-22231260
Coord C2 exon
chr7:22206691-22206766
Length
114 bp
Sequences
Splice sites
3' ss Seq
TATTCTTGCTTTCTTCTCAGTTA
3' ss Score
8.21
5' ss Seq
GGGGTTGGT
5' ss Score
0.32
Exon sequences
Seq C1 exon
ATATGTGGTGGTGTCCGGGACCCCGGAGAAGATTTTGGAGCACCTTTTGAATGACTTGCACCTGGAAGAAGTCCAGGACAAAGAAACAG
Seq A exon
TTATACCAACCCCTGGGATCACATGTGTCACTTCTGCCATGTGCTCACAAAGCCAAGCGGACCAGGACTTCATGGCTTGACTCTCCTAGCACCAACCTAAGTGGGGAAGAAGGG
Seq C2 exon
AGACCCTCCTGGATGACTTCCTTCTCACGTACACTGTCTTCATGACAACTGATGACTTGTGCCAGGCTCTGTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136237_MULTIEX1-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.087 A=0.212 C2=0.000
Domain overlap (PFAM):
C1:
PF0061815=RasGEF_N=PU(25.5=90.3)
A:
NO
C2:
PF0061815=RasGEF_N=PD(46.3=92.6)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATATGTGGTGGTGTCCGGGAC
R:
TAACAGAGCCTGGCACAAGTC
Band lengths:
163-277
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)