HsaEX0056642 @ hg38
Exon Skipping
Gene
ENSG00000136193 | SCRN1
Description
secernin 1 [Source:HGNC Symbol;Acc:HGNC:22192]
Coordinates
chr7:29955179-29969068:-
Coord C1 exon
chr7:29968909-29969068
Coord A exon
chr7:29966327-29966415
Coord C2 exon
chr7:29955179-29955360
Length
89 bp
Sequences
Splice sites
3' ss Seq
TTTGATTTTTACATGGGCAGATT
3' ss Score
5.86
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
GATGGCTGCAGCTCCTCCAAGTTACTGTTTTGTTGCCTTCCCTCCACGTGCTAAGGATGGTCTGGTGGTATTTGGGAAAAATTCAGCCCGGCCCAGAGATGAAGTGCAAGAGGTTGTGTATTTCTCGGCTGCTGATCACGAACCGGAGAGCAAGGTTGAG
Seq A exon
ATTTAAGTTCTCAAAGGTGGCTGCACCAAATCCCATCCCAAGTGCCCTTCTTCCAGTGTGAAGGGCACTCCTTCCACGAAGAGGGAAAG
Seq C2 exon
TGCACTTACATTTCAATCGACCAAGTTCCAAGGACCTATGCCATAATGATAAGCAGACCCGCCTGGCTCTGGGGAGCAGAAATGGGAGCCAATGAACATGGAGTGTGCATAGCCAATGAAGCCATCAACACCAGAGAGCCAGCTGCCGAGATAGAAGCCTTGCTGGGGATGGATCTGGTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136193_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.023 A=1.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0357710=Peptidase_C69=PU(15.7=64.2)
A:
NO
C2:
PF0357710=Peptidase_C69=PU(23.3=80.4)
Main Inclusion Isoform:
ENST00000242059fB6148
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACCGGAGAGCAAGGTTGAG
R:
CAAGGCTTCTATCTCGGCAGC
Band lengths:
183-272
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development