HsaEX0073715 @ hg19
Exon Skipping
Gene
ENSG00000124459 | ZNF45
Description
zinc finger protein 45 [Source:HGNC Symbol;Acc:13111]
Coordinates
chr19:44416781-44423114:-
Coord C1 exon
chr19:44423022-44423114
Coord A exon
chr19:44420051-44420082
Coord C2 exon
chr19:44416781-44419352
Length
32 bp
Sequences
Splice sites
3' ss Seq
CCATAAACCTCTTCTCCCAGGTG
3' ss Score
7.35
5' ss Seq
GAGGTAAAG
5' ss Score
8.27
Exon sequences
Seq C1 exon
GGCATCAGTCCACACCAGATGGCCTACCACAGTTAGAGAGAGAAGAAAAGCTGTGGATGATGAAGATGGCAACCCAGAGAGATAACTCCTCAG
Seq A exon
GTGTTCTCATGGAGGCTATTTCCTAGCAAGAG
Seq C2 exon
GAGCCAAGAATCTAAAAGAGATGGAGACTCTTCAAGAAGTAGGATTAAGGTACCTGCCTCATGAAGAGCTTTTCTGCTCCCAGATCTGGCAACAGATTACAAGAGAGTTAATCAAGTATCAAGATTCTGTGGTAAATATTCAAAGAACAGGCTGCCAGTTGGAAAAACGAGATGATTTGCACTATAAAGATGAGGGATTCAGTAATCAGAGTTCCCATCTTCAAGTTCACAGAGTCCACACTGGTGAAAAACCCTACAAAGGAGAACATTGTGTGAAAAGTTTCAGCTGGAGCTCTCATCTTCAAATTAACCAAAGGGCTCATGCAGGAGAGAAGCCCTACAAATGTGAAAAATGTGATAATGCCTTCCGTCGGTTTTCAAGTCTTCAAGCCCATCAGAGAGTCCACAGTAGAGCAAAATCATACACAAATGATGCAAGTTACAGGAGTTTTAGTCAGAGGTCACATCTTCCCCATCATCAGAGAGTTCCCACTGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124459-'11-14,'11-13,12-14
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion (Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.411 A=0.000 C2=0.124
Domain overlap (PFAM):
C1:
PF0135222=KRAB=PD(0.1=0.0)
A:
NO
C2:
PF0009621=zf-C2H2=WD(100=3.8),PF134651=zf-H2C2_2=WD(100=4.6),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.0),PF134651=zf-H2C2_2=WD(100=4.3),PF0013017=C1_1=WD(100=7.9),PF134651=zf-H2C2_2=WD(100=4.1),PF134651=zf-H2C2_2=WD(100=4.1)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGTGGATGATGAAGATGGCA
R:
GCTCTTCATGAGGCAGGTACC
Band lengths:
113-145
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)