HsaEX0073847 @ hg19
Exon Skipping
Gene
ENSG00000175322 | ZNF519
Description
zinc finger protein 519 [Source:HGNC Symbol;Acc:30574]
Coordinates
chr18:14104720-14124475:-
Coord C1 exon
chr18:14124349-14124475
Coord A exon
chr18:14108121-14108235
Coord C2 exon
chr18:14104720-14106408
Length
115 bp
Sequences
Splice sites
3' ss Seq
AGACTGTCCTTTCCTCGAAGGTC
3' ss Score
7.1
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
GAACTCTTAACATTCAGGGATGTGGCCATAGAATTCTCTCCAGAAGAGTGGAAATGCCTAGACCCTGCCCAACAGAATTTATATAGAGATGTGATGTTGGAGAACTACAGAAACCTCGTCTCCCTGG
Seq A exon
GTCGAGTTTCACCAAGGACCCATCCCTGCCTGCCTAGGAGTTTGTCTTCTGTCACTATCAGTAGGACTGCAGTGGGTCAGACCTGAAACCAGCACAGCAGTTGATCACACCCAAG
Seq C2 exon
CTGTGTATTCTTATTACAACCAAGGCATTTTACCAGAGCAAGGCATACAAGATTCATTCAAAAAAGCAACACTGGGAAGATATGGGAGCTGTGGCCTTGAAAATATATGCTTATGGAAAAACTGGGAAAGTATAGGTGAAGGTGAAGGACAAAAGGAATGTTATAATCTATGTAGCCAATATTTGACAACTAGTCATAACAAACATTTAACTGTGAAAGGAGACAAAGAATATAGAATATTTCAGAAGAAGCCTCAGTTTCTGTCAGCTGCTCCTACAGAACCATGTATTCCTATGAATAAATATCAACATAAATTTTTGAAATCTGTCTTTTGTAATAAAAATCAGATAAATTTTAACCATGACTCAAATATTAGTAAACATCATAGTACTCATTTTCTAGAAAACTATTACAATTGTAATGAATGTGAAAAAGTATTTTACCAATCCTCAAAGCTTATTTTCCCTGAAAATATCCATATTCAAAAAAAGCCTTACAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175322-'1-2,'1-1,2-2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion (Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.082
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=95.3)
A:
PF0135222=KRAB=PD(0.1=0.0)
C2:
PF0135222=KRAB=PD(0.1=0.0),PF134651=zf-H2C2_2=WD(100=4.6),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.0),PF134651=zf-H2C2_2=WD(100=5.2),PF134651=zf-H2C2_2=WD(100=5.2)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCCAGAAGAGTGGAAATGCC
R:
CCTTTTGTCCTTCACCTTCACCT
Band lengths:
247-362
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)