HsaEX1001197 @ hg38
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9089912-9091412:-
Coord C1 exon
chr12:9091201-9091412
Coord A exon
chr12:9090356-9090482
Coord C2 exon
chr12:9089912-9090023
Length
127 bp
Sequences
Splice sites
3' ss Seq
TTTCTTATGTGTGGTTTCAGGTC
3' ss Score
10.69
5' ss Seq
TAGGTGAGC
5' ss Score
7.96
Exon sequences
Seq C1 exon
AGGTAGGAGTAACAGTCCCTGACACCATCACCGAGTGGAAGGCAGGGGCCTTCTGCCTGTCTGAAGATGCTGGACTTGGTATCTCTTCCACTGCCTCTCTCCGAGCCTTCCAGCCCTTCTTTGTGGAGCTCACAATGCCTTACTCTGTGATTCGTGGAGAGGCCTTCACACTCAAGGCCACGGTCCTAAACTACCTTCCCAAATGCATCCGG
Seq A exon
GTCAGTGTGCAGCTGGAAGCCTCTCCCGCCTTCCTAGCTGTCCCAGTGGAGAAGGAACAAGCGCCTCACTGCATCTGTGCAAACGGGCGGCAAACTGTGTCCTGGGCAGTAACCCCAAAGTCATTAG
Seq C2 exon
GAAATGTGAATTTCACTGTGAGCGCAGAGGCACTAGAGTCTCAAGAGCTGTGTGGGACTGAGGTGCCTTCAGTTCCTGAACACGGAAGGAAAGACACAGTCATCAAGCCTCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899-'55-48,'55-47,56-48
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.146
Domain overlap (PFAM):
C1:
PF0020717=A2M=FE(83.5=100)
A:
PF0020717=A2M=PD(4.4=9.3)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACACCATCACCGAGTGGAAG
R:
TCAGTCCCACACAGCTCTTGA
Band lengths:
253-380
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains