HsaEX1004541 @ hg38
Exon Skipping
Gene
ENSG00000180448 | ARHGAP45
Description
Rho GTPase activating protein 45 [Source:HGNC Symbol;Acc:HGNC:17102]
Coordinates
chr19:1077857-1079840:+
Coord C1 exon
chr19:1077857-1078045
Coord A exon
chr19:1078084-1078943
Coord C2 exon
chr19:1079127-1079840
Length
860 bp
Sequences
Splice sites
3' ss Seq
AGGGCTGGAGGTCCCTGGAGGAG
3' ss Score
-11.5
5' ss Seq
GAGGCCGAG
5' ss Score
-11.86
Exon sequences
Seq C1 exon
CAAGAGGCGGAGTCCAACCTGCGCAAGGCCAAGCAGGGTTACGTGCAGCGCTGCGAGGACCACGACAAGGCTCGCTTCCTCGTGGCCAAGGCGGAGGAGGAGCAGGCTGGCAGCGCGCCGGGAGCAGGCAGCACGGCCACCAAGACCCTGGACAAGCGGCGGCGGCTGGAGGAGGAGGCCAAGAACAAG
Seq A exon
GAGGAGATCCAATGCTTGGTGTGACATTTACTACCTCCAGACCTTTGTTTTTGTTTTTTTGTTTTTTTGTTTGTTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACAGTCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGTCCACCTCGGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCACTGCGCCCGGCCAATTTGTTTTTTGGAGACAGAGTCTCATTCTGTTGCCCAGGCTGGAGTGCAGTGGTGAGATCTCACTGCAACCTCCGCCTCCCAGGTTCACACAGTTCTCTGCCTCAGCCACCCTGCCACCAAGCCCAGCTAATTTTTTTGTATTTTTAGTAGACACAGAGTTTCACCATCTTGGCCAGGTTGGTCTCAAACTCCTGACCTCATGATCCACCCACTTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCCCGATTTTTAAATTATTATTATTTTTGAGACAGTGTCTTGTTCTGTCACCCAGGCTGGAGTGCAGTGACGTGATCATGGCTCACTGCAGCCTCTACCTCCTGGGCTCAAGCAATCTTCTCGCCTCAGCCTCTAGAGTAGCTGGGACCACAGGCGTGTGCCGCCACACCCAGCTAATTTAAAAAAATTCTTGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAG
Seq C2 exon
CCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAACGAGACTCTGTCTCAAAAAAAAAAAAAAATTCTTTATAAAGATGGGGGTCTCAGGCTGAGTGTGGTGGCTCACACCTGTAATCCCAGCCCTTTGGGAGGCTGAGACGGGCAGATCATATGAGGCCAGGAGTTCGAAACCAGCCTGGGCAACATGGTGAAACCCCTGTATCTCTACTAAAATTACAAAAAATTAACCGGGTATGGTGGGTGGGGGGCACCTGTAATCCGTTACTTGGGAGGCTGAGGCAGAATTGCTTGAACCCGGTAGGTGGAGGTTGCAGTGAGCTGAGATCGTACCACTGCACTCCAGCCTGGCCTACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAGATGGGGAGGGTCTCACCATGTTGCTCAGGCTGGTCTCGAACTCCTGGCCTCAAGCAAGTCTCCCACTGTGGCCTCCCGAGGCGCTGGGATGACAGGCGTCAGCCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000180448-'30-35,'30-34,31-35
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.782 A=0.000 C2=0.428
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000313093fB9766
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGAGGAGGCCAAGAACAAG
R:
ACGATCTCAGCTCACTGCAAC
Band lengths:
355-1215
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains