HsaEX1010909 @ hg38
Exon Skipping
Gene
ENSG00000186526 | CYP4F8
Description
cytochrome P450 family 4 subfamily F member 8 [Source:HGNC Symbol;Acc:HGNC:2648]
Coordinates
chr19:15615616-15618144:+
Coord C1 exon
chr19:15615616-15615814
Coord A exon
chr19:15616977-15617229
Coord C2 exon
chr19:15618000-15618144
Length
253 bp
Sequences
Splice sites
3' ss Seq
GCCGCTGTTCTTCCTGACAGACA
3' ss Score
9.66
5' ss Seq
AAGGTGGGC
5' ss Score
7.93
Exon sequences
Seq C1 exon
GATGTCGCTGCTGAGCCTGTCTTGGCTGGGCCTCAGGCCGGTGGCAGCATCCCCGTGGCTGCTCCTGCTGGTGGTCGGGGCCTCCTGGCTCCTGGCCCGCATCCTGGCCTGGACCTATGCCTTCTATCACAACGGCCGCCGCCTCCGGTGTTTCCCGCAGCCCCGGAAACAGAACTGGTTCTTGGGTCACCTGGGCCTG
Seq A exon
ACAGTTAGAGCCACCTCTTCTCCCCTGGGGGCTGCTGAGAAAGGAAGTTCCACCGTGTACAGACCTTCTCCATGGGAGGGCCTGGGGCCCCTGAGGCCCAGCCAGGACATAAAAGGATGTGGGGACCAGCCCTGGGGACATGTCCTGAGGCCACATTGCTGCCCACACACCACACTTGTGGAGCCCACCCCACGTGACTTTCCGTGGGCTGGAGCCACTCCCAGGATGAGAAAATCCATCCTCTTTATTCAAG
Seq C2 exon
GTCACTCCCACAGAGGAGGGCTTGAGGGTCCTGACCCAGCTGGTGGCCACCTACCCCCAGGGCTTTGTGAGGTGGTTGGGCCCCATCACTCCCATCATCAACTTGTGCCACCCTGACATCGTCCGATCTGTCATCAATACCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186526-'2-2,'2-1,3-2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.188 C2=0.272
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(3.0=21.2)
A:
NO
C2:
PF0006717=p450=FE(10.3=100)
Main Inclusion Isoform:
ENST00000612078fB13382
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGCTGAGCCTGTCTTGG
R:
CAGGGTGGCACAAGTTGATGA
Band lengths:
308-561
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains