HsaEX1012092 @ hg38
Exon Skipping
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]
Coordinates
chr1:172038319-172042144:+
Coord C1 exon
chr1:172038319-172038461
Coord A exon
chr1:172040677-172040918
Coord C2 exon
chr1:172042009-172042144
Length
242 bp
Sequences
Splice sites
3' ss Seq
CTGTGCCAAATGCTCTGCAGGAA
3' ss Score
7.99
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
CAACTTACCAACCACATTCGGGATACCCTACCAAACTTCAGGAACAAACTACAGGGACAGTTGCTCTCCATAGAACATGAAGTAGAAGCCTACAAAAATTTCAAACCAGAAGACCCAACAAGGAAGACCAAAGCATTGCTGCA
Seq A exon
GAAACACGCTGAAGATGCAGAGGAGGGGCGATGAGGAGTGGTGCCGGATAGAGTCATGGATCATGAAAAGTTTCTGGGAAGAACCAATGCTTGAGCTGAGTCTTAAAGAACACGTAAAAATTAGTCAGGCAAAGCAGCAAGGGACAGAGAGAATGGTGTTCTGAGCAGAAAGAAAAGTGTAAAAGCACAGGGACATGGTGCATTTGGGGAACTGCAATGGCTTCCTTATGGTTGGCTGGAAG
Seq C2 exon
GATGGTTCAGCAATTTGCTGTGGACTTTGAGAAGAGAATTGAAGGGTCAGGGGATCAAGTAGATACCCTGGAACTCTCAGGTGGTGCTAAAATCAATCGTATTTTTCATGAACGCTTTCCTTTTGAGATAGTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959_MULTIEX3-3/6=2-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.243 A=1.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(15.9=100)
A:
PF0103115=Dynamin_M=PD(5.7=58.3)
C2:
PF0103115=Dynamin_M=FE(15.3=100)
Main Inclusion Isoform:
ENST00000355305fB14095
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAACTTACCAACCACATTCGGGA
R:
TACTATCTCAAAAGGAAAGCGTTCA
Band lengths:
276-518
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains