HsaEX1012378 @ hg38
Exon Skipping
Gene
ENSG00000171587 | DSCAM
Description
DS cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:3039]
Coordinates
chr21:40144491-40167288:-
Coord C1 exon
chr21:40167218-40167288
Coord A exon
chr21:40166487-40166579
Coord C2 exon
chr21:40144491-40144731
Length
93 bp
Sequences
Splice sites
3' ss Seq
CACATCGTTTCATTCAACAGCCA
3' ss Score
6.64
5' ss Seq
CAGGTCAGT
5' ss Score
8.94
Exon sequences
Seq C1 exon
CTCCTGATGGTCCACCTCAGGAAGTTCACCTGGAGCCTATATCATCTCAGAGCATCAGGGTCACATGGAAG
Seq A exon
CCATGGTTTCCATAGCAAATTTTCTCAAGTAAGGAAGCAGTGTTGATTCTGGAGCAAGCTCATCACCAACCACCACTGTTCCATGGCCTTCAG
Seq C2 exon
GCTCCCAAGAAACATTTGCAAAATGGGATTATCCGTGGCTACCAAATAGGTTACCGAGAGTACAGCACTGGGGGTAACTTCCAATTCAACATTATCAGTGTCGACACCAGCGGGGACAGTGAGGTTTACACCCTGGACAACCTGAATAAGTTCACTCAGTACGGCCTGGTGGTGCAGGCCTGTAACCGGGCCGGCACGGGGCCTTCTTCTCAGGAAATCATCACCACCACTCTCGAGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000171587-'48-43,'48-42,49-43
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.592 A=0.000 C2=0.142
Domain overlap (PFAM):
C1:
PF0004116=fn3=PU(22.0=83.3)
A:
NO
C2:
PF0004116=fn3=PD(75.8=85.2)
Main Inclusion Isoform:
ENST00000400454fB14300
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTCCACCTCAGGAAGTTCA
R:
CGCTGGTGTCGACACTGATAA
Band lengths:
176-269
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains