HsaEX1016866 @ hg38
Exon Skipping
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]
Coordinates
chr2:74882120-74885589:+
Coord C1 exon
chr2:74882120-74882239
Coord A exon
chr2:74882972-74883107
Coord C2 exon
chr2:74885494-74885589
Length
136 bp
Sequences
Splice sites
3' ss Seq
TGCTTCTCACTCCTCTTCAGGTT
3' ss Score
9.82
5' ss Seq
TAGGTATCT
5' ss Score
4.28
Exon sequences
Seq C1 exon
CTCTTTGACCACATTGTCCAGTGCATCGCGGACTTCCTCGAGTACATGGGCATGAAGGGCGTGTCCCTGCCTCTGGGTTTTACCTTCTCCTTCCCCTGCCAGCAGAACAGCCTGGACGAG
Seq A exon
GTTACCTTGGGTGAATGAAGTAGGTGCATGAGGATCTGGCACTCCCAGATGTTCTGGACATGAGTGCCCCGAGAAGTGGAGGAGAACTGAGTAGGCAGTGCTGGATCTGCTGATGACTGGTAGCCCTAAGCATTAG
Seq C2 exon
AGCATCCTCCTCAAGTGGACAAAAGGCTTCAAGGCATCTGGCTGCGAGGGCGAGGACGTGGTGACCCTGCTGAAGGAAGCGATCCACCGGCGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399_MULTIEX1-3/3=2-C2
Average complexity
C1
Mappability confidence:
75%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=FE(18.9=100)
A:
PF0034916=Hexokinase_1=PD(2.6=66.7)
C2:
PF0034916=Hexokinase_1=FE(15.0=100)
Main Inclusion Isoform:
ENST00000290573fB17110
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGACCACATTGTCCAGTGCA
R:
CTCGCCGGTGGATCGCTT
Band lengths:
210-346
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains